{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:37:23Z","timestamp":1785411443145,"version":"3.56.0"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"unspecified","delay-in-days":168,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Antiparasitic agents are routinely used in companion animal medicine. However, longitudinal evidence describing real-world usage patterns in dogs remains limited. This study aimed to characterise patterns, routes of administration, temporal trends, and seasonal variation in antiparasitic drug use among Golden Retrievers enrolled in a large prospective cohort study in the United States. A descriptive analysis was conducted to summarise antiparasitic usage data from the Morris Animal Foundation\u2019s Golden Retriever Lifetime Study over nine study years (corresponding to years 0 to 8). Percentages with respective 95% CI were used to summarise drug types, therapy combinations, routes of administration, and temporal and seasonal patterns of use. A total of 17,715 antiparasitic use records were analysed. Drug usage pattern was highly concentrated within a limited number of products, with the ivermectin\u2013pyrantel pamoate combination accounting for 23.0% of all recorded use. Other commonly used agents included afoxolaner (9.73%), metronidazole (9.16%), and lufenuron\u2013milbemycin oxime (8.95%). Oral formulations were predominant, representing 65.28% of all administrations. Single-agent therapy accounted for 47.27% of use, while two-drug combination therapy represented 46.65%. The antiparasitic medications spanned multiple pharmacological classes targeting both endo- and ectoparasites, including anthelmintics, ectoparasiticides, and antiprotozoals. Antiparasitic use declined by 1.8% over the study period. We observed a seasonal variation in antiparasitic drug usage, with higher usage during cooler months (winter) and lower use in summer. These findings provide baseline evidence of the burden of endoparasites and ectoparasites in Golden Retriever dogs and highlight the need for stewardship-oriented parasite control strategies in companion animal practice.<\/jats:p>","DOI":"10.1017\/s0022149x26101710","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T08:01:11Z","timestamp":1781769671000},"source":"Crossref","is-referenced-by-count":0,"title":["Patterns of antiparasitic usage in Golden Retriever breed of dogs: A 9-year cohort study"],"prefix":"10.1017","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0300-1474","authenticated-orcid":false,"given":"M. J.","family":"Oladoye","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0405mnx93","id-type":"ROR","asserted-by":"publisher"}],"name":"Texas Tech University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Awosile","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0405mnx93","id-type":"ROR","asserted-by":"publisher"}],"name":"Texas Tech University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7850-9104","authenticated-orcid":false,"given":"O.","family":"Adekoya","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0405mnx93","id-type":"ROR","asserted-by":"publisher"}],"name":"Texas Tech University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Rodriguez-Mori","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0405mnx93","id-type":"ROR","asserted-by":"publisher"}],"name":"Texas Tech University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7145-6162","authenticated-orcid":false,"given":"O.","family":"Akinkuotu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0405mnx93","id-type":"ROR","asserted-by":"publisher"}],"name":"Texas Tech University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,18]]},"reference":[{"key":"S0022149X26101710_r7","doi-asserted-by":"publisher","DOI":"10.12968\/coan.2023.0034"},{"key":"S0022149X26101710_r15","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2004.08.001"},{"key":"S0022149X26101710_r21","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2024.1377718"},{"key":"S0022149X26101710_r1","first-page":"221","article-title":"Seasonal fluctuations in prevalence of dog intestinal parasites in public squares of Mar del Plata city, Argentina and its risk for humans","volume":"39","author":"Andresiuk","year":"2007","journal-title":"Revista Argentina de Microbiolog\u00eda"},{"key":"S0022149X26101710_r2","unstructured":"Campbell, S and Soman-Faulkner, K (2025) Antiparasitic Drugs. In StatPearls. Treasure Island (FL): StatPearls Publishing. ###a href=\u201dhttps:\/\/www.ncbi.nlm.nih.gov\/books\/NBK544251\/\u201d target=\u201d _blank\u201d>https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK544251\/ (accessed )"},{"key":"S0022149X26101710_r13","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-021-04766-7"},{"key":"S0022149X26101710_r4","first-page":"1159","article-title":"Isoxazolines for treating canine demodicosis, sarcoptic mange (scabies), and lice infestation","volume":"63","author":"Defalque","year":"2022","journal-title":"Canadian Veterinary Journal"},{"key":"S0022149X26101710_r8","doi-asserted-by":"publisher","DOI":"10.2478\/acve-2023-0004"},{"key":"S0022149X26101710_r12","article-title":"The Golden Retriever Lifetime Study: establishing an observational cohort study with translational relevance for human health","volume":"370","author":"Guy","year":"2015","journal-title":"Philosophical Transactions of the Royal Society of London. 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