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Hyg."],"published-print":{"date-parts":[[1974,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>In a maternity hospital in which the umbilicus and trunk of healthy newborn infants were treated with 0\u00b733% hexachlorophane dusting powder, the hexachlorophane content of blood was measured in mothers before delivery, in infants' umbilical samples at birth, and at 8 days of age in capillary blood samples. One mother and her baby had rather high blood concentrations of hexachlorophane, probably derived from a toilet preparation used before admission to hospital. Hexachlorophane was absent or barely detectable in the other mothers' blood and in the infants' umbilical blood. The hexachlorophane concentrations in the blood of 8-day-old infants ranged from nil to 0\u00b7166<jats:italic>\u03bc<\/jats:italic>g.\/ml. (mean 0\u00b7066<jats:italic>\u03bc<\/jats:italic>g.\/ml.). These were much less than the concentrations reported to be toxic in animals.<\/jats:p><jats:p>In a previous trial now reported here, a dusting powder containing chlorhexidine instead of hexachlorophane was found to delay the separation of the umbilical cord.<\/jats:p>","DOI":"10.1017\/s0022172400024177","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T10:01:09Z","timestamp":1242381669000},"page":"311-315","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Absorption of hexachlorophane from dusting powder on newborn infants' skin"],"prefix":"10.1017","volume":"73","author":[{"given":"W. A.","family":"Gillespie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beryl D.","family":"Corner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Burman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. G.","family":"Alder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0022172400024177_ref013","doi-asserted-by":"crossref","first-page":"519","DOI":"10.5694\/j.1326-5377.1963.tb25155.x","article-title":"Antisepsis and staphylococcal disease in the new-born child","volume":"ii","author":"Pleuckhahn","year":"1963","journal-title":"Medical Journal of Australia"},{"key":"S0022172400024177_ref012","doi-asserted-by":"crossref","first-page":"93","DOI":"10.5694\/j.1326-5377.1973.tb119650.x","article-title":"Infant antiseptic skin care and hexachlorophane","volume":"i","author":"Pleuckhahn","year":"1973","journal-title":"Medical Journal of Australia"},{"key":"S0022172400024177_ref011","unstructured":"Hart E. R. (1971). Toxicity of pHisoHex on 90-day skin applications to infant rhesus monkeys, report submitted to Sterling\u2013Winthrop Research Institute by Bionetics Research Laboratories, December 3. (Cited by Pleuckhahn, 1973.)"},{"key":"S0022172400024177_ref008","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1542\/peds.51.2.413","article-title":"Staphylococcal disease outbreaks in hospital nurseries in the United States \u2013 December 1971 through March 1972","volume":"51","author":"Dixon","year":"1973","journal-title":"Pediatrics"},{"key":"S0022172400024177_ref007","unstructured":"Curley A. & Hawk R. E. (1971). Hexachlorophene I. Analysis in body fluids and tissues of experimental animals, paper read at 161st National Meeting of the American Chemical Society, Los Angeles. March 28 to April 2. 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