{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T15:06:07Z","timestamp":1726412767052},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":22233,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J. Hyg."],"published-print":{"date-parts":[[1948,7]]},"abstract":"<jats:p>1. An outbreak of typhoid fever in a Royal Air Force camp in the Middle East is discussed.<\/jats:p><jats:p>2. A total of 110 cases occurred of which 105 are analysed. The case-fatality rate was 10%.<\/jats:p><jats:p>3. Of the 105 cases 59% gave a positive blood culture. The percentages of diagnostic isolations from stools and urine were small.<\/jats:p><jats:p>4. Clearance tests of stools and urine showed that 8.4% of patients excreted<jats:italic>Salm. typhi<\/jats:italic>during convalescence.<\/jats:p><jats:p>5. Leucocyte counts during the first 2 weeks of the illness showed that only 30% of the patients had a count below 5000 per cu.mm.; 62% of these low figures were encountered in severe cases.<\/jats:p><jats:p>6. Autopsies on seven fatal cases showed considerable variability in the macroscopic appearance of the intestinal lesions.<\/jats:p><jats:p>7. Serological investigation confirmed that higher percentages of cases with low titres of O agglutinin were found in the severe and mild clinical groups, and that most O titres in the moderately severe cases exceeded 1:200.<\/jats:p><jats:p>8. Of the patients 52% showed Vi titres exceeding 1:20 during convalescence.<\/jats:p><jats:p>9. 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