{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T20:10:41Z","timestamp":1648584641864},"reference-count":3,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":16511,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J. Hyg."],"published-print":{"date-parts":[[1964,3]]},"abstract":"<jats:p>Eight carriers of intestinal pathogens (5 <jats:italic>Salm. typhi-murium<\/jats:italic>, 2 <jats:italic>Sh. sonnei<\/jats:italic>, 1 <jats:italic>E. coli<\/jats:italic> 026) were given their own coliforms, rendered drug-resistant <jats:italic>in vitro<\/jats:italic> to neomycin or paromomycin, together with one of these drugs. In seven cases, the drug-resistant coliform flora established itself, while the natural coliform flora and the pathogen were suppressed. In four cases only (<jats:italic>2 Sh. sonnei<\/jats:italic>, 2 <jats:italic>Salm. typhi-murium<\/jats:italic>) the pathogen was eliminated in the course of this procedure.<\/jats:p>","DOI":"10.1017\/s0022172400039759","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T10:28:23Z","timestamp":1242383303000},"page":"39-44","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Replacement coliform flora in carriers of intestinal pathogens"],"prefix":"10.1017","volume":"62","author":[{"given":"G. T","family":"Stewart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. J","family":"Holt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. M. T","family":"Coles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. M","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0022172400039759_ref001","first-page":"379","article-title":"Paromomycin","volume":"186","author":"Coles","year":"1961","journal-title":"Practitioner"},{"key":"S0022172400039759_ref002","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5246.200"},{"key":"S0022172400039759_ref003","first-page":"36","article-title":"Gradient plates for the study of microbial resistance to antibiotics","author":"Szybalski","year":"1952","journal-title":"Bact. Proc."}],"container-title":["Journal of Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022172400039759","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T20:33:08Z","timestamp":1559593988000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022172400039759\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,3]]},"references-count":3,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1964,3]]}},"alternative-id":["S0022172400039759"],"URL":"https:\/\/doi.org\/10.1017\/s0022172400039759","relation":{},"ISSN":["0022-1724"],"issn-type":[{"value":"0022-1724","type":"print"}],"subject":[],"published":{"date-parts":[[1964,3]]},"assertion":[{"value":"Cambridge University Press 1964","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}