{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:25:02Z","timestamp":1756992302383,"version":"3.37.0"},"reference-count":7,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":16419,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J. Hyg."],"published-print":{"date-parts":[[1964,6]]},"abstract":"<jats:p>Complement-fixation tests with psittacosis-trachoma group antigens, if set up with complement prepared from guinea-pigs cross-infected with any of the Bedsonia agents, may give completely false positive results. The use of C.F. positive or C.F. inhibition positive samples of guinea-pig sera as a source of complement can induce also a significant increase or decrease, respectively, of the actual C.F. titres in Bedsonia-positive serum samples tested. Observations made both in routine serology and in experimental studies show the necessity of testing carefully, for possible presence of Bedsonia titres, individual sera of guinea-pigs intended for use as source of complement in C.F. tests performed with Bedsonia group antigens.<\/jats:p><jats:p>I have pleasure in thanking Dr F. B. Gordon and Dr E. Weiss for the valuable suggestions made and HM3 C.O. Wiese for the technical assistance.<\/jats:p>","DOI":"10.1017\/s0022172400039917","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T10:28:51Z","timestamp":1242383331000},"page":"179-184","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["\u2018False positive\u2019 complement fixation with psittacosis\u2014trachoma antigens due to antibodies in complement preparations"],"prefix":"10.1017","volume":"62","author":[{"given":"Alexander L.","family":"Terzin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0022172400039917_ref006","doi-asserted-by":"crossref","first-page":"90","DOI":"10.4049\/jimmunol.85.1.90","article-title":"Different types of serologic reactivity to Bedsonia (psittacosis group) antigen in various hosts","volume":"85","author":"Terzin","year":"1960","journal-title":"J. Immunol."},{"key":"S0022172400039917_ref005","first-page":"36","article-title":"The complement fixation inhibition test as a serological tool in the virus laboratory","volume":"2","author":"Terzin","year":"1958","journal-title":"J. Hyg. Epidemiol. (Praha)"},{"volume-title":"Experimental Immunochemistry","year":"1961","author":"Kabat","key":"S0022172400039917_ref002"},{"volume-title":"Viral and Rickettsial Diseases of Man","year":"1959","author":"Meyer","key":"S0022172400039917_ref003"},{"doi-asserted-by":"publisher","key":"S0022172400039917_ref004","DOI":"10.1093\/infdis\/114.1.1"},{"key":"S0022172400039917_ref007","first-page":"78","article-title":"Preparation of group-specific Bedsonia antigens for use in complement-fixation reactions","volume":"5","author":"Terzin","year":"1961","journal-title":"Acta virol., Prague"},{"key":"S0022172400039917_ref001","first-page":"114","article-title":"Technique of complement fixation test","volume":"7","author":"Hoyle","year":"1948","journal-title":"Mon. Bull. Minist. Hlth Lab. Serv."}],"container-title":["Journal of Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022172400039917","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T12:31:45Z","timestamp":1739104305000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022172400039917\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,6]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1964,6]]}},"alternative-id":["S0022172400039917"],"URL":"https:\/\/doi.org\/10.1017\/s0022172400039917","relation":{},"ISSN":["0022-1724"],"issn-type":[{"type":"print","value":"0022-1724"}],"subject":[],"published":{"date-parts":[[1964,6]]},"assertion":[{"value":"Cambridge University Press 1964","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}