{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T14:25:52Z","timestamp":1794407152548,"version":"4.9.0"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":12402,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J. Hyg."],"published-print":{"date-parts":[[1975,6]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>In a study on a Caucasian population in Western Australia the prevalence of antibodies to Epstein\u2013Barr virus (EBV) was 41% in the 9- to 10-year age group, 80% in the 16 to 19-year age group and 92% in young adults. The age-specific annual seroconversion rates indicated two peaks of primary EBV infection in the population studied \u2013 one under 5 years of age and the other at adolescence. The geometric mean titre rose with age, from 23 at 5\u20136 years to 53 at 36\u201340 years.<\/jats:p><jats:p>It was shown that in 73 families studied there was evidence of probable spread of EBV infection among siblings, particularly between those of the same sex.<\/jats:p><jats:p>Serological study of patients with infectious mononucleosis indicated that 100% of those examined had antibody to EBV and the geometric mean titre was elevated to 210. Rising titres and seroconversion was demonstrated in these patients together with successful establishment of EBV-carrying cell lines from the peripheral blood in two-thirds of the cases.<\/jats:p>","DOI":"10.1017\/s0022172400046842","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:55:36Z","timestamp":1242381336000},"page":"329-337","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":27,"title":["Epidemiological studies of Epstein\u2013Barr herpesvirus infection in Western Australia"],"prefix":"10.1017","volume":"74","author":[{"given":"P. K.","family":"Lai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. M.","family":"Mackay-Scollay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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