{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T20:34:07Z","timestamp":1696624447105},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"unspecified","delay-in-days":11732,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J. Hyg."],"published-print":{"date-parts":[[1977,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A series of outbreaks of skin sepsis among meat handlers in England during 1974 and 1975 afforded an opportunity to study the group-A streptococci commonly isolated from the lesions. Few of these streptococci could be M typed with existing antisera. Intensive study of strains from two outbreaks of sepsis in one abattoir in Shropshire led to the recognition of three new provisional M types. The streptococci were first sorted according to T-typing pattern and ability to produce opacity factor. Opacity-factor producing strains with the same T pattern were then screened for inhibition of opacity production by the sera of convalescents from the same outbreak. Finally, M antisera were made in rabbits against representative cultures.<\/jats:p><jats:p>Sera against the three new provisional types were used to re-examine streptococci from 20 other outbreaks or incidents of sporadic infection among meat handlers. This increased the proportion of typable strains from 3% to 55%. Two of the new provisional types (nos. 2015 and 1658; both T25\/Imp 19, opacity-factor positive) were confined to the Shropshire outbreak, but the third (no. 2681; T14, opacity-factor negative) was found among strains from meat workers in eight other geographically distinct areas. In all, 31% of 131 distinct strains from meat workers, but less than 1% of 2816 strains from other British sources, belonged to provisional type 2681. Thus, in Britain, one M-type of group-A streptococcus appears at present to be almost exclusively associated with sepsis in meat workers.<\/jats:p>","DOI":"10.1017\/s0022172400056175","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T05:50:53Z","timestamp":1242366653000},"page":"283-296","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":17,"title":["Serological characterization of group-A streptococci associated with skin sepsis in meat handlers"],"prefix":"10.1017","volume":"78","author":[{"given":"Cherry A. M.","family":"Fraser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lyn C.","family":"Ball","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. A.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. D.","family":"Noah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"S0022172400056175_ref012","first-page":"153","article-title":"Laboratory diagnosis of streptococcal infection","volume":"19","author":"Williams","year":"1958","journal-title":"Bulletin of the World Health Organization"},{"key":"S0022172400056175_ref010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197001012820106"},{"key":"S0022172400056175_ref009","doi-asserted-by":"publisher","DOI":"10.1084\/jem.134.5.1298"},{"key":"S0022172400056175_ref007","first-page":"526","article-title":"Skin infections in meat handlers","volume":"i","year":"1975","journal-title":"British Medical Journal"},{"key":"S0022172400056175_ref005","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-6-1-83"},{"key":"S0022172400056175_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400046180"},{"key":"S0022172400056175_ref003","first-page":"111","article-title":"An epizootic in Swiss mice caused by group A streptococcus, newly designated type 50","volume":"72","author":"Hook","year":"1960","journal-title":"American Journal of Hygiene"},{"key":"S0022172400056175_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)90303-0"},{"key":"S0022172400056175_ref001","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/126.3.294"},{"key":"S0022172400056175_ref008","first-page":"583","article-title":"Skin infections in meat handlers","volume":"i","year":"1975","journal-title":"British Medical Journal"},{"key":"S0022172400056175_ref011","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-61-3-343"},{"key":"S0022172400056175_ref013","first-page":"46","article-title":"The type classification of Streptococcus pyogenes","volume":"1","author":"Williams","year":"1953","journal-title":"Atti del VI Congresso Internazionale di Microbiologia Roma"},{"key":"S0022172400056175_ref006","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400000966"}],"container-title":["Journal of Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022172400056175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T15:16:43Z","timestamp":1559056603000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022172400056175\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,4]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1977,4]]}},"alternative-id":["S0022172400056175"],"URL":"https:\/\/doi.org\/10.1017\/s0022172400056175","relation":{},"ISSN":["0022-1724"],"issn-type":[{"value":"0022-1724","type":"print"}],"subject":[],"published":{"date-parts":[[1977,4]]},"assertion":[{"value":"Cambridge University Press 1977","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}