{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:27:01Z","timestamp":1761708421823},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T00:00:00Z","timestamp":1255910400000},"content-version":"unspecified","delay-in-days":9515,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J. Hyg."],"published-print":{"date-parts":[[1983,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A single application of the male chemosterilant, \u03b1-chlorhydrin, to a problem sewer rat infestation resulted in reductions of rat numbers and distribution which was comparable to effects of warfarin baiting methods. Rat numbers were reduced by more than 85% by both methods. More rapid mortality and recruitment were evident for warfarin effects; the \u03b1-chlorhydrin treated population had a longer lag phase of growth so that reinfestation of sewer habitat to pre-treatment numbers, and distribution over a 40 square block area, required approximately 1\u00b75\u20132 times longer after \u03b1-chlorhydrin treatment when compared with warfarin treatment. Comparisons of changes in rat densities in infested sewers following the two treatments indicate that recovery of warfarin treated populations is achieved by reproductive recruitment followed by dispersal while \u03b1-chlorhydrin treated populations recover by slower immigration and later reproductive recruitment. Alpha-chlorohydrin should be a useful addition to a limited arsenal of rat control agents because of its specificity for the Norway rat, its single dose effectiveness as a toxicant-chemosterilant, and its short environmental half-life.<\/jats:p>","DOI":"10.1017\/s0022172400060381","type":"journal-article","created":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T09:01:37Z","timestamp":1255942897000},"page":"359-366","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":10,"title":["Efficacy of alpha-chlorhydrin in sewer rat control"],"prefix":"10.1017","volume":"91","author":[{"given":"R. V.","family":"Andrews","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. W.","family":"Belknap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,10,19]]},"reference":[{"key":"S0022172400060381_ref013","first-page":"309","article-title":"Prospects of chemosterilant and genetic control of rodenta","volume":"48","author":"Marsh","year":"1973","journal-title":"Bulletin of the World Health Organisation"},{"key":"S0022172400060381_ref011","doi-asserted-by":"publisher","DOI":"10.2307\/3798854"},{"key":"S0022172400060381_ref006","first-page":"469","article-title":"A critical review of currently used single-dose rodenticides","volume":"48","author":"Gratz","year":"1973","journal-title":"Bulletin of the World Health Organisation"},{"key":"S0022172400060381_ref002","first-page":"40","article-title":"An effective application of U-5897 to the control of established feral rats","volume":"60","author":"Andrews","year":"1975","journal-title":"Nebraska Medical Journal"},{"key":"S0022172400060381_ref001","doi-asserted-by":"publisher","DOI":"10.2307\/3800058"},{"key":"S0022172400060381_ref008","first-page":"319","article-title":"Effects of U-5897 on fine structure of the rat epididymus","volume":"166","author":"Hoffer","year":"1970","journal-title":"Analytical Record"},{"key":"S0022172400060381_ref010","first-page":"12","article-title":"Anti-coagulant resistance in Norway rata as found in U.S. cities","volume":"43","author":"Jackson","year":"1975","journal-title":"Pest Control"},{"key":"S0022172400060381_ref007","doi-asserted-by":"publisher","DOI":"10.2307\/3798855"},{"key":"S0022172400060381_ref012","doi-asserted-by":"publisher","DOI":"10.2307\/3799660"},{"key":"S0022172400060381_ref009","doi-asserted-by":"publisher","DOI":"10.2307\/3799843"},{"key":"S0022172400060381_ref003","doi-asserted-by":"publisher","DOI":"10.2307\/3799765"},{"key":"S0022172400060381_ref005","first-page":"100","article-title":"Principles of population control by gametocides","volume":"26","author":"Davis","year":"1961","journal-title":"Transactions of the. North American Wild and Natural Resources Conference"},{"key":"S0022172400060381_ref004","first-page":"3","article-title":"Effects of Norbormide on sewer rats","volume":"13","author":"Brooks","year":"1966","journal-title":"Californian Vector News"}],"container-title":["Journal of Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022172400060381","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T18:23:46Z","timestamp":1558635826000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022172400060381\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,10]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1983,10]]}},"alternative-id":["S0022172400060381"],"URL":"https:\/\/doi.org\/10.1017\/s0022172400060381","relation":{},"ISSN":["0022-1724"],"issn-type":[{"value":"0022-1724","type":"print"}],"subject":[],"published":{"date-parts":[[1983,10]]},"assertion":[{"value":"Cambridge University Press 1983","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}