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Hyg."],"published-print":{"date-parts":[[1982,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>One hundred and five shigella isolates from Addis Ababa were studied to determine serogroup frequency and<jats:italic>in vitro<\/jats:italic>antibacterial drug sensitivity.<\/jats:p><jats:p>About 70 % of the isolates were<jats:italic>Shigella Flexneri<\/jats:italic>followed by<jats:italic>Sh. dysenteriae<\/jats:italic>(15%),<jats:italic>Sh. boydii<\/jats:italic>(10%) and<jats:italic>Sh. sonnei<\/jats:italic>(5%). All or most of the strains were susceptible to cephalothin, gentamicin, kanamycin, polymyxin B and trimetho-primsulphamethoxazole. Frequencies of susceptibility to ampicillin, carbenicillin and chloramphenicol were, respectively, 79, 80 and 75%. Only 37, 23 and 58% were susceptible to streptomycin, sulphadiazine and tetracycline, respectively.<\/jats:p><jats:p>Resistance to one or more drugs was detected in 85 % while 72 % were multiply resistant. There were 24 different resistance patterns, varying from resistance to one drug to resistance to seven drugs.<\/jats:p><jats:p>The findings have been compared with reports from other countries. This study and several others cited support the view that trimethoprim-sulphamethoxazole is the best alternative drug for treatment of shigellosis particularly in regions with multiple drug-resistant strains.<\/jats:p>","DOI":"10.1017\/s0022172400069886","type":"journal-article","created":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T13:15:31Z","timestamp":1269522931000},"page":"47-55","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["<i>Shigella<\/i>species from Addis Ababa: frequency of isolation and<i>in vitro<\/i>drug sensitivity"],"prefix":"10.1017","volume":"88","author":[{"given":"Messele","family":"Gedebou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alebachew","family":"Tassew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2010,3,25]]},"reference":[{"key":"S0022172400069886_ref017","first-page":"123","article-title":"Bacterial isolates at Black Lion Hospital: their frequency of isolation and drug susceptibility patterns. 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