{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:10:17Z","timestamp":1791277817394,"version":"4.1.0"},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T00:00:00Z","timestamp":1269475200000},"content-version":"unspecified","delay-in-days":10037,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["J. Hyg."],"published-print":{"date-parts":[[1982,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Trials of rodenticidal baits containing 50 p.p.m. difenacoum, 50 p.p.m. bromadiolone or 20 p.p.m. brodifacoum were carried out on farmsteads against populations of <jats:italic>Rattus norvegicus<\/jats:italic> containing difenacoum-resistant individuals. Six difenacoum treatments failed in 14\u201342 days of baiting. Two treatments with bromadiolone succeeded in 23 and 33 days, but four further treatments lasting 35\u201356 days failed to eradicate the populations. Brodifacoum gave virtually complete control of six populations in 21\u201373 days and of the ten residual populations left behind by the other two compounds, after baiting for a further 11\u201385 days. The performance of both bromadiolone and brodifacoum was well below that reported by previous investigators, indicating the possibility of low-grade resistance to these compounds in the difenacoum-resistant strain.<\/jats:p>","DOI":"10.1017\/s0022172400070820","type":"journal-article","created":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T13:12:28Z","timestamp":1269522748000},"page":"295-301","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":42,"title":["Field trials of second-generation anticoagulants against difenacoum-resistant Norway rat populations"],"prefix":"10.1017","volume":"89","author":[{"given":"J. H.","family":"Greaves","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. S.","family":"Shepherd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Quy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,3,25]]},"reference":[{"key":"S0022172400070820_ref010","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400069126"},{"key":"S0022172400070820_ref009","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400053419"},{"key":"S0022172400070820_ref007","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400055807"},{"key":"S0022172400070820_ref006","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400026760"},{"key":"S0022172400070820_ref005","first-page":"503","article-title":"New rodenticides against anticoagulant-resistant rats and mice","volume":"7","author":"Lund","year":"1977","journal-title":"Bulletin of the European and Mediterranean Plant Protection Organization"},{"key":"S0022172400070820_ref004","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-7348.1982.tb01425.x"},{"key":"S0022172400070820_ref002","first-page":"239","article-title":"The detection of rodent resistance to anticoagulants","volume":"48","author":"Drummond","year":"1973","journal-title":"Bulletin of the World Health Organization"},{"key":"S0022172400070820_ref001","doi-asserted-by":"publisher","DOI":"10.1038\/150059a0"},{"key":"S0022172400070820_ref003","unstructured":"Dubock A. C. & Kaukeinen D. E. (1978). Brodifacoum (Talon rodenticide), a novel concept.Proceedings of the 8th Vertebrate Pest Conference,Sacramento, California, 127\u2013137."},{"key":"S0022172400070820_ref008","doi-asserted-by":"publisher","DOI":"10.1002\/ps.2780080418"}],"container-title":["Journal of Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022172400070820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T20:34:15Z","timestamp":1558730055000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022172400070820\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,10]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1982,10]]}},"alternative-id":["S0022172400070820"],"URL":"https:\/\/doi.org\/10.1017\/s0022172400070820","relation":{},"ISSN":["0022-1724"],"issn-type":[{"value":"0022-1724","type":"print"}],"subject":[],"published":{"date-parts":[[1982,10]]},"assertion":[{"value":"Cambridge University Press 1982","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}