{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T17:38:14Z","timestamp":1760204294227},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":8033,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1985,7]]},"abstract":"<jats:p>Abstract Eighty-eight patients from 16 to 79 years old, with acute purulent otitis media, were bacteriologically examined at the Otorhinolaryngology Department of a primary care hospital in Tokyo from July 1979 to May 1983. Fifty-six patients underwent paracentesis, and 32 patients exhibited otorrhea due to previous spontaneous perforation of the tympanic membrane.<\/jats:p><jats:p>Bacteriologic cultures revealed the presence of<jats:italic>Streptococcus pneumoniae<\/jats:italic>(62.5 per cent), including<jats:italic>S. pneumoniae Type III<\/jats:italic>(28.1 per cent),<jats:italic>Haemophilus influenzae<\/jats:italic>(10.5 per cent),<jats:italic>Staphylococcus aureus<\/jats:italic>(11.5 per cent), and<jats:italic>Streptococcus pyogenes<\/jats:italic>(7.3 per cent).<jats:italic>S. pneumoniae Type III<\/jats:italic>had a notably high detection rate in patients from 50 to 79 years old (50\u201375 per cent). Because<jats:italic>Haemophilus influenzae<\/jats:italic>was detected at a relatively high rate in patients of all ages, if can be considered as a was detected at a relatively high rate in patients of all ages, if can be considered as a major causative pathogen of AOM.<\/jats:p><jats:p>In 44 patients, selected mainly from those who underwent paracentesis, a comparative study of bacteria found in middle ear fluid and naso-pharyngeal mucus revealed the same nacteria in 43 out of 44 cases. (97.7 per cent), indicating the presence of bacterial infection through the auditory canal.<\/jats:p><jats:p>Antibiotics were selected according to an Expected Efficiacy Index (EEI), the antibiotic of first choice being Ampicillin or Cefaclor.<\/jats:p>","DOI":"10.1017\/s0022215100097395","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:24:45Z","timestamp":1196418285000},"page":"629-635","source":"Crossref","is-referenced-by-count":11,"title":["Bacteriological features and chemotherapy of adult acute purulent otitis media"],"prefix":"10.1017","volume":"99","author":[{"given":"Rinya","family":"Sugita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Fujimaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Deguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100097395_ref003","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100088630"},{"key":"S0022215100097395_ref014","doi-asserted-by":"publisher","DOI":"10.5631\/jibirin.75.921"},{"key":"S0022215100097395_ref012","first-page":"568","article-title":"A bacteriological investigation of acute otitis media","volume":"82","author":"Sugita","year":"1979","journal-title":"Journal of Otolaryngology of Japan"},{"key":"S0022215100097395_ref001","volume-title":"Bergey's Manual of Determinative Bacteriology","author":"Buchanan","year":"1977"},{"key":"S0022215100097395_ref015","first-page":"751","article-title":"Bacterial coincidence in the infected middle ear and nasopharynx","volume":"82","author":"Sugita","year":"1979","journal-title":"Journal of Otolaryngology of Japan"},{"key":"S0022215100097395_ref016","first-page":"1381","article-title":"Chemotherapy of acute otitis media","volume":"82","author":"Sugita","year":"1979","journal-title":"Journal of Otolaryngology of Japan"},{"key":"S0022215100097395_ref004","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1542\/peds.45.1.29","article-title":"Otitis media: A clinical and bacteriological correlation","volume":"45","author":"Howie","year":"1970","journal-title":"Pediatrics"},{"key":"S0022215100097395_ref008","volume-title":"Studies of the Aetiology of Acute Otitis Media","author":"Nielsen","year":"1945"},{"key":"S0022215100097395_ref005","first-page":"617","article-title":"Bacteriological studies of acute otitis media","volume":"16","author":"Itoh","year":"1934","journal-title":"Journal of Keio University Medical Society"},{"key":"S0022215100097395_ref009","doi-asserted-by":"publisher","DOI":"10.3109\/00016488209130903"},{"key":"S0022215100097395_ref007","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1542\/peds.17.3.359","article-title":"A bacteriologic investigation of otitis media in infancy","volume":"17","author":"Mortimer","year":"1956","journal-title":"Pediatrics"},{"key":"S0022215100097395_ref010","first-page":"107","article-title":"Bacteriological study on acute otitis media","volume":"37","author":"Sarashina","year":"1941","journal-title":"Japanese Journal of Hygiene and Infectious Diseases"},{"key":"S0022215100097395_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(81)80004-X"},{"key":"S0022215100097395_ref017","first-page":"1591","article-title":"Otitis media in pediatric practice","volume":"64","author":"Townsend","year":"1964","journal-title":"New York State Journal of Medicine"},{"key":"S0022215100097395_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(83)80114-1"},{"key":"S0022215100097395_ref002","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1980.03300480048027"},{"key":"S0022215100097395_ref006","doi-asserted-by":"publisher","DOI":"10.1007\/BF01582640"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100097395","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T01:16:43Z","timestamp":1684113403000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100097395\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,7]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1985,7]]}},"alternative-id":["S0022215100097395"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100097395","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,7]]}}}