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The disorders found could be classified as mild bleeding disorders (MBD) and compared to the estimated frequency of MBD in the population there was an increased incidence of haemostatic disorders in the habitual nose-bleeders. Abnormal vessels in the nasal mucosa were present in 85 per cent of the investigated nose-bleeders, equaly distributed between nose-bleeders with and without haemostatic disorders. This indicates that abnormal vessels and haemostatic disorders occur independently of each other. When screening for haemostatic disorders in habitual nose-bleeders, it is possible to detect previously unknown but clinically important disorders.<\/jats:p>","DOI":"10.1017\/s0022215100103160","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:22:50Z","timestamp":1196418170000},"page":"1020-1028","source":"Crossref","is-referenced-by-count":17,"title":["Haemostatic disorders in habitual nose-bleeders"],"prefix":"10.1017","volume":"101","author":[{"given":"Martin","family":"Beran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennart","family":"Stigendal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Petruson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100103160_ref032","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197506192922502"},{"key":"S0022215100103160_ref034","first-page":"1240","article-title":"High frequency of haemorrhagic complications in anticoagulant therapy","volume":"82","author":"Svensson","year":"1985","journal-title":"L\u00e4kartidningen"},{"key":"S0022215100103160_ref033","first-page":"185","article-title":"Elec-trophoretic heterogeneity of normal factor VIII, von Willebrand's protein and abnormal electrophoretic mobility in patients with von Willebrand's disease","volume":"87","author":"Sultan","year":"1976","journal-title":"Journal of Laboratory and Clinical Medicine"},{"key":"S0022215100103160_ref035","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107465"},{"key":"S0022215100103160_ref030","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)32427-0"},{"key":"S0022215100103160_ref029","first-page":"249","volume-title":"Platelets in biology and pathology","author":"Santoro","year":"1981"},{"key":"S0022215100103160_ref028","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198005083021902"},{"key":"S0022215100103160_ref023","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1973.01620190047011"},{"key":"S0022215100103160_ref020","first-page":"64","volume-title":"measurements of platelet function","author":"Kinlough-Rathbone","year":"1983"},{"key":"S0022215100103160_ref019","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80757-9"},{"key":"S0022215100103160_ref015","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1970.tb01615.x"},{"key":"S0022215100103160_ref013","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.42.2.128"},{"key":"S0022215100103160_ref008","doi-asserted-by":"publisher","DOI":"10.1159\/000205234"},{"key":"S0022215100103160_ref005","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1963.sp007185"},{"key":"S0022215100103160_ref009","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-89-6-921"},{"key":"S0022215100103160_ref031","first-page":"85","article-title":"von Willebrand's disease in Sweden","author":"Silver","year":"1973","journal-title":"Acta paediatrica Scandinavica"},{"key":"S0022215100103160_ref002","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/62.6.856"},{"key":"S0022215100103160_ref004","doi-asserted-by":"publisher","DOI":"10.1159\/000275886"},{"key":"S0022215100103160_ref016","first-page":"215","article-title":"A one-stage factor VIII (antihaemophilic globulin) assay and its use on venous and capillary plasma","volume":"7","author":"Hardisty","year":"1962","journal-title":"Thrombosis et Diathesis Haemorrhagica"},{"key":"S0022215100103160_ref017","first-page":"1","article-title":"The adhesiveness of human blood platelets in vitro","volume":"12","author":"Hellem","year":"1960","journal-title":"Scandinavian Journal of Clinical and Laboratory Investigation"},{"key":"S0022215100103160_ref012","first-page":"342","article-title":"The enigma of severe factor XI deficiency without hemor-rhagic symptoms","volume":"18","author":"Edson","year":"1967","journal-title":"Thrombosis et Diathesis Haemorrhagica"},{"key":"S0022215100103160_ref010","doi-asserted-by":"crossref","DOI":"10.1111\/j.0954-6820.1968.tb10458.x","article-title":"Investigations in haemorrhagic disorders with prolonged bleeding time but normal number of platelets","author":"Cronberg","year":"1968","journal-title":"Acta Medica Scandinavica"},{"key":"S0022215100103160_ref036","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107464"},{"key":"S0022215100103160_ref021","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1970.tb08046.x"},{"key":"S0022215100103160_ref001","first-page":"292","article-title":"Diagnostic approach to mild bleeding disorders","volume":"17","author":"Bachmann","year":"1980","journal-title":"Seminars in Hematology"},{"key":"S0022215100103160_ref006","first-page":"1714","article-title":"Evaluation of new capillary resistometer; 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