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In each case the finding of anti-neutrophil cytoplasm antibodies (ANCA) strongly suggested an underlying vasculitic pathology, Wegener's granulomatosis. We discuss reasons for the difficulty in diagnosis in the past, the possible role of the ANCA assay in such patients, and suggest it should be more widely used in the future.<\/jats:p>","DOI":"10.1017\/s0022215100111314","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T05:20:31Z","timestamp":1196400031000},"page":"1187-1191","source":"Crossref","is-referenced-by-count":25,"title":["Wegener's granulomatosis, subglottic stenosis and antineutrophil cytoplasm antibodies."],"prefix":"10.1017","volume":"103","author":[{"given":"T. J.","family":"Hoare","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Jayne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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