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A case is reported in which a diabetic male with advanced mucormycosis was successfully treated by a combination of surgery, supportive therapy and liposomal amphotericin B. Liposomal delivery allows the drug to be both less toxic and more effective, and this is the first reported case of its use in rhinocerebral mucormycosis.<\/jats:p>","DOI":"10.1017\/s0022215100116652","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:18:58Z","timestamp":1196417938000},"page":"575-577","source":"Crossref","is-referenced-by-count":75,"title":["Rhinocerebral mucormycosis: Use of liposomal amphotericin B"],"prefix":"10.1017","volume":"105","author":[{"given":"Edward W.","family":"Fisher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbad","family":"Toma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip H.","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony D.","family":"Cheesman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100116652_ref027","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198909000-00023"},{"key":"S0022215100116652_ref022","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1958.00730020739010"},{"key":"S0022215100116652_ref020","first-page":"615","volume-title":"Medical Mycology","author":"Rippon","year":"1982"},{"key":"S0022215100116652_ref015","first-page":"1576","article-title":"Use of liposomes as injectable drug delivery systems","volume":"46","author":"Ostro","year":"1989","journal-title":"American Journal of Hospital Pharmacy"},{"key":"S0022215100116652_ref005","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198004000-00010"},{"key":"S0022215100116652_ref026","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197708000-00012"},{"key":"S0022215100116652_ref006","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1288\/00005537-196509000-00002","article-title":"Mucormycosis of the nose and paranasal sinuses","volume":"75","author":"De Weese","year":"1965","journal-title":"Laryngoscope"},{"key":"S0022215100116652_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510009410X"},{"key":"S0022215100116652_ref021","first-page":"717","volume-title":"Principles and Practice of Rhinology","author":"Shugar","year":"1987"},{"key":"S0022215100116652_ref018","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198809010-00005"},{"key":"S0022215100116652_ref008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1990.tb00377.x"},{"key":"S0022215100116652_ref025","first-page":"155","volume-title":"Fungal Infections in the Compromised Patient","author":"Wong","year":"1982"},{"key":"S0022215100116652_ref004","doi-asserted-by":"publisher","DOI":"10.1177\/000348947007900107"},{"key":"S0022215100116652_ref011","first-page":"585","volume-title":"Otolaryngology\u2013Head and Neck Surgery","volume":"1","author":"Hill","year":"1986"},{"key":"S0022215100116652_ref003","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/0002-9343(55)90194-7","article-title":"Cerebral mucormycosis: pathogenesis of the disease","volume":"18","author":"Baver","year":"1955","journal-title":"American Journal of Medicine"},{"key":"S0022215100116652_ref023","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1979.00790160046012"},{"key":"S0022215100116652_ref016","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198603000-00004"},{"key":"S0022215100116652_ref024","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(89)90111-4"},{"key":"S0022215100116652_ref001","first-page":"254","article-title":"Liposomes as drug carriers","volume":"26","author":"Alpar","year":"1989","journal-title":"Pharmaceutical Journal"},{"key":"S0022215100116652_ref010","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1961.01840020216010"},{"key":"S0022215100116652_ref013","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.31.5.675"},{"key":"S0022215100116652_ref019","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198005000-00002"},{"key":"S0022215100116652_ref012","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-105-1-130"},{"key":"S0022215100116652_ref009","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.160.1.3715034"},{"key":"S0022215100116652_ref017","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1977.00780270068011"},{"key":"S0022215100116652_ref014","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1989.00390110097022"},{"key":"S0022215100116652_ref007","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009900216"}],"container-title":["The Journal of Laryngology &amp; 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