{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:04:22Z","timestamp":1767675862898},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":5689,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1991,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present a British series of eleven patients with primary cholesteatoma, including one patient with bilateral disease. Eight children presented with a history of hearing loss, while one child had had recurrent otitis media and another had had carache. Operative findings were: in five ears, cholesteatoma confined to the antero-superior segment with intact ossicles, in a further four, cholesteatomas extending throughout the mesotympanum with ossicular erosion in one, and in two ears posterior disease throughout the middle ear and mastoid, which had eroded the ossicles in both cases. The five cases of antero-superior cholesteatoma lend most support to Michaels' concept of epidermoid formation as a possible source of congenital cholesteatoma. With a greater awareness of the problem and careful examination of the antero-superior quadrant of the tympanic membrane, earlier diagnosis may be possible enabling removal of small intact cholesteatoma sacs and preserving the structures of the middle ear and therefore the hearing.<\/jats:p><jats:p>A screening programme for infants included as part of their routine examination which would be undertaken by examiners who are trained to be more aware of the problem and skilled at otoscopy, would help in the earlier detection of such cases as is shown by reports from the U.S.A.<\/jats:p>","DOI":"10.1017\/s0022215100118043","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:18:21Z","timestamp":1196417901000},"page":"995-998","source":"Crossref","is-referenced-by-count":9,"title":["Congenital cholesteatoma"],"prefix":"10.1017","volume":"105","author":[{"given":"B.","family":"Laskiewicz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Chalstrey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. J.","family":"Gatland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Michaels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100118043_ref016","doi-asserted-by":"publisher","DOI":"10.3109\/00016485909129191"},{"key":"S0022215100118043_ref019","first-page":"323","article-title":"Congenital tympanic cholesteatoma","volume":"55","author":"Wingert","year":"1976","journal-title":"Ear, Nose and Throat Journal"},{"key":"S0022215100118043_ref009","first-page":"169","article-title":"An epidermoid formation in the developing middle ear: possible source of cholesteatoma","volume":"15","author":"Michaels","year":"1986","journal-title":"Journal of Otolaryngology"},{"key":"S0022215100118043_ref014","first-page":"48","article-title":"Amniotic fluid contents in the ears of neonates and infants","volume":"1","author":"Piza","year":"1985","journal-title":"XIII World Congress of Otorhinolaryngology (Abstract)"},{"key":"S0022215100118043_ref018","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198411000-00013"},{"key":"S0022215100118043_ref002","first-page":"61","article-title":"Location of primary cholesteatoma","volume":"8","author":"Cohen","year":"1987","journal-title":"American Journal of Otology"},{"key":"S0022215100118043_ref003","unstructured":"Cruveilhier (1829) Anatomic Pathologique T. II."},{"key":"S0022215100118043_ref005","first-page":"557","article-title":"A large epidermal cholesteatoma of the parieto-temporal region deforming the left hemisphere without cerebral symptoms","volume":"34","author":"Cushing","year":"1922","journal-title":"Surgery, Gynaecology and Obstetrics"},{"key":"S0022215100118043_ref012","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0030-6665(20)32576-7","article-title":"Congenital cholesteatoma","volume":"11","author":"Paparella","year":"1978","journal-title":"Otolaryngologic Clinics of North America"},{"key":"S0022215100118043_ref001","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198309000-00005"},{"key":"S0022215100118043_ref013","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1975.00780370040015"},{"key":"S0022215100118043_ref008","doi-asserted-by":"publisher","DOI":"10.1177\/000348948409300619"},{"key":"S0022215100118043_ref007","doi-asserted-by":"publisher","DOI":"10.1177\/019459988609400605"},{"key":"S0022215100118043_ref006","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-195308000-00004"},{"key":"S0022215100118043_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(88)90050-X"},{"key":"S0022215100118043_ref011","first-page":"22","article-title":"Evolution of the epidermoid formation and its role in the development of the middle ear and tympanic membrane during the first trimester","volume":"17","author":"Michaels","year":"1988","journal-title":"Journal of Otolaryngology"},{"key":"S0022215100118043_ref004","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197907000-00016"},{"key":"S0022215100118043_ref017","doi-asserted-by":"publisher","DOI":"10.3109\/00016488309132882"},{"key":"S0022215100118043_ref015","unstructured":"Ruben R. (1989) Efficacy of early diagnosis of primary cholesteatoma in infants. Proceedings of Third International Conference in Cholesteatoma and Mastoid Surgery."}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100118043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T13:10:47Z","timestamp":1630242647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100118043\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,12]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1991,12]]}},"alternative-id":["S0022215100118043"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100118043","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,12]]}}}