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The characteristics of the tumour cells and the tumourhost relationship were scored on H &amp; E-stained slides, as well as on slides stained with a panel of antibodies. The results obtained were cross-tabulated and analysed with respect to the subsite. Ten variables were tested: cytonuclear pleomorphism, mitotic activity, the presence of atypical mitoses, keratinization, tumour grade, presence of eosinophils, severity of inflammatory response, and the expression of keratin-10, blood group antigens and collagen IV. When split up by site, only cytonuclear pleomorphism revealed a significant difference, tonsillar carcinomas more often exhibiting marked pleomorphism (p=0.04).<\/jats:p><jats:p>Despite having some prognostic relevance for squamous cell carcinomas of the head and neck, the variables tested could not provide an explanation for the difference in biological behaviour of the tumours studied.<\/jats:p>","DOI":"10.1017\/s0022215100125472","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T05:16:39Z","timestamp":1196399799000},"page":"1129-1135","source":"Crossref","is-referenced-by-count":0,"title":["Squamous cell carcinoma of the tonsillar region and the base of the tongue: a morphological and immunohistochemical comparative pilot study"],"prefix":"10.1017","volume":"107","author":[{"given":"Sanja","family":"Mak-Kregar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolter J.","family":"Mooi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfons J. 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