{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:05:28Z","timestamp":1767981928455,"version":"3.49.0"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":4927,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1994,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report on two patients who have high titres of antiphospholipid antibodies, both of whom had acute audiovestibular failure. One of the patients had systemic lupus erythematosus. The other patient had primary antiphospholipid syndrome: audiovestibular symptoms have not been reported in this condition. The occurrence of acute audiovestibular failure in the primary antiphospholipid syndrome raises the question as to whether patients presenting with acute deafness or vestibular disturbance should be screened for the presence of anticardiolipin antibodies.<\/jats:p>","DOI":"10.1017\/s0022215100125848","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:16:27Z","timestamp":1196417787000},"page":"57-59","source":"Crossref","is-referenced-by-count":30,"title":["Audiovestibular manifestations of the antiphospholipid syndrome"],"prefix":"10.1017","volume":"108","author":[{"given":"Tim","family":"Vyse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda M.","family":"Luxon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.","family":"Walport","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100125848_ref001","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1055\/s-0038-1660103","article-title":"The dilute phospholipid activated partial thromboplastin time: a sensitive assay for the verification of lupus anticoagulant","volume":"54","author":"Alving","year":"1985","journal-title":"Thrombosis Haemostasis"},{"key":"S0022215100125848_ref002","doi-asserted-by":"publisher","DOI":"10.1136\/ard.46.8.605"},{"key":"S0022215100125848_ref016","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0307-742X(21)00606-8","article-title":"Anti-phospholipid antibodies","volume":"11","author":"Harris","year":"1985","journal-title":"Clinics in Rheumatic Diseases"},{"key":"S0022215100125848_ref023","doi-asserted-by":"publisher","DOI":"10.1136\/ard.48.5.362"},{"key":"S0022215100125848_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)91267-9"},{"key":"S0022215100125848_ref004","first-page":"805","article-title":"Vestibular findings in vertebrobasilar ischaemia","volume":"80","author":"Barber","year":"1971","journal-title":"Annals of Otology"},{"key":"S0022215100125848_ref025","first-page":"57","article-title":"Autoimmune disease and cochlear pathology in the C3H\/lpr strain mouse","volume":"89","author":"Trumer","year":"1989","journal-title":"Hearing Research"},{"key":"S0022215100125848_ref009","doi-asserted-by":"crossref","first-page":"843","DOI":"10.7326\/0003-4819-19-6-843","article-title":"Acute lupus erythematosus disseminata","volume":"19","author":"Cluxton","year":"1943","journal-title":"Annals of Internal Medicine"},{"key":"S0022215100125848_ref015","first-page":"47","article-title":"Cerebral infarction in systemic lupus: association with anticardiolipin antibodies","volume":"2","author":"Harris","year":"1984","journal-title":"Clinical and Experimental Rheumatology"},{"key":"S0022215100125848_ref022","first-page":"738","article-title":"Measurement of anticardiolipin antibody by an enzyme-linked immunosorbent assay (ELISA): standardization and quantification of results","volume":"62","author":"Loizou","year":"1985","journal-title":"Clinical and Experimental Immunology"},{"key":"S0022215100125848_ref003","doi-asserted-by":"publisher","DOI":"10.1136\/ard.48.5.358"},{"key":"S0022215100125848_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(86)90179-0"},{"key":"S0022215100125848_ref012","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.6.446"},{"key":"S0022215100125848_ref018","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.15.1.114"},{"key":"S0022215100125848_ref006","first-page":"571","article-title":"Chorea and systemic lupus erythematosus with circulating lupus anticoagulant. Three cases","volume":"14","author":"Bouchez","year":"1985","journal-title":"Reviews in Neurology (Paris)"},{"key":"S0022215100125848_ref013","doi-asserted-by":"publisher","DOI":"10.1177\/000348947608500117"},{"key":"S0022215100125848_ref026","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198906000-00007"},{"key":"S0022215100125848_ref005","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0272-2712(18)30690-5","article-title":"Autoimmunity and otologic disease: clinical and experimental aspects","volume":"8","author":"Barna","year":"1988","journal-title":"Clinical and Laboratory Medicine"},{"key":"S0022215100125848_ref010","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1984.00350150102029"},{"key":"S0022215100125848_ref007","first-page":"210","article-title":"Sensorineuronal hearing loss in lupus erythematosus","volume":"7","author":"Calderelli","year":"1984","journal-title":"American Journal of Otology"},{"key":"S0022215100125848_ref011","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197607000-00004"},{"key":"S0022215100125848_ref020","doi-asserted-by":"publisher","DOI":"10.1177\/000348945806700101"},{"key":"S0022215100125848_ref017","unstructured":"Harris E. N. , Chan J. K. H. , Asherson R. A. , Aber V. R. , Gharavi A. E. , Hughes G. R. V. (1986)"},{"key":"S0022215100125848_ref019","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196807000-00002"},{"key":"S0022215100125848_ref021","first-page":"254","article-title":"Lupus anticoagulants and thrombosis","volume":"15","author":"Lechner","year":"1985","journal-title":"Haemostasis"},{"key":"S0022215100125848_ref024","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100113179"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100125848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T13:07:37Z","timestamp":1630242457000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100125848\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,1]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1994,1]]}},"alternative-id":["S0022215100125848"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100125848","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,1]]}}}