{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:12:32Z","timestamp":1761487952886},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":4654,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1994,10]]},"abstract":"<jats:p>Abstract: Primary extramedullary plasmacytoma (PEP) is an uncommon neoplasm of plasma cell origin which afflicts the head and neck mainly. In this study we report a rare case of a 34-year-old man who presented with left ear tinnitus, hearing loss, blocked feeling and headache. Exploratory tympanotomy revealed a mass extending into the attic and the mastoid antrum. Following canal wall-up mastoidectomy, the tumour was carefully removed. Histological examination (including immunoperoxidase staining) and thorough clinical, laboratory and radiological evaluation revealed an exclusively cytoplasmic monoclonal IgG immunoglobulin PEP. The combination of surgery (including a second-look procedure) and radiotherapy used in this case may be an over-treatment. However, the patient is still disease-free seven years after his first admission to hospital.<\/jats:p>","DOI":"10.1017\/s002221510012835x","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:15:51Z","timestamp":1196417751000},"page":"868-870","source":"Crossref","is-referenced-by-count":13,"title":["Primary extramedullary plasmacytoma in the middle ear: differential diagnosis and management"],"prefix":"10.1017","volume":"108","author":[{"given":"D. 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