{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T15:10:50Z","timestamp":1726758650736},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":4593,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1994,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The ultrastructural details of normal middle ear mucosa have been reported in detail in the literature. This study was aimed at investigating the superficial structure of middle ear epithelium with the scanning electron microscope in patients with persistent otitis media with effusion (OME) and chronic suppurative otitis media (CSOM), especially in the light of the authors' recent findings regarding decreased ciliary beat frequency (CBF) in patients exposed to tobacco smoke.<\/jats:p><jats:p>Mucosal biopsies were taken from the anterior mesotympanum in four patients with OME and another four patients with CSOM. There was no significant abnormality of cellular surface structure in patients with chronic middle ear disease. Furthermore, no significant difference was observed between smoke exposed and nonsmoke exposed patients. It is concluded that the effect of tobacco smoke on CBF is functional and not related to any anatomical abnormality observed by scanning electron microscopy (SEM).<\/jats:p>","DOI":"10.1017\/s0022215100128828","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:15:40Z","timestamp":1196417740000},"page":"1024-1030","source":"Crossref","is-referenced-by-count":4,"title":["Surface morphology of middle ear epithelium in chronic ear disease"],"prefix":"10.1017","volume":"108","author":[{"given":"A. M.","family":"Agius","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Wake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. L.","family":"Pahor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. A.","family":"Smallman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100128828_ref014","first-page":"203","article-title":"Distribution of ciliated cells in the human middle ear","volume":"81","author":"Shimada","year":"1972","journal-title":"Annals of Otology"},{"key":"S0022215100128828_ref005","doi-asserted-by":"publisher","DOI":"10.3109\/00016487209138958"},{"key":"S0022215100128828_ref006","doi-asserted-by":"publisher","DOI":"10.3109\/00016487209138967"},{"key":"S0022215100128828_ref011","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1973.00780020006002"},{"key":"S0022215100128828_ref015","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790340001001"},{"key":"S0022215100128828_ref009","first-page":"57","article-title":"Human middle ear epithelium","volume":"89","author":"Lim","year":"1969","journal-title":"Archives of Otolaryngology"},{"key":"S0022215100128828_ref012","first-page":"131","volume-title":"The Nose: Upper Airway Physiology and the Atmospheric Environment","author":"Proctor","year":"1982"},{"key":"S0022215100128828_ref002","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195711\/12)10:6<1246::AID-CNCR2820100623>3.0.CO;2-Z"},{"key":"S0022215100128828_ref010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1979.tb01888.x"},{"key":"S0022215100128828_ref008","first-page":"125","article-title":"Ultrastructure of normal human middle ear mucosa","volume":"78","author":"Kawabata","year":"1969","journal-title":"Annals of Otology"},{"key":"S0022215100128828_ref007","first-page":"306","article-title":"Ultrastructure of middle ear mucosa and organization of ciliary matrix","volume":"80","author":"Hilding","year":"1971","journal-title":"Annals of Otology"},{"key":"S0022215100128828_ref004","first-page":"16","volume-title":"Muir's Textbook of Pathology","author":"Heath","year":"1985"},{"key":"S0022215100128828_ref001","unstructured":"Agius A. M. , Wake M. , Pahor A. L. , Smallman L. A. (in press) Smoking and middle ear ciliary beat frequency in otitis media with effusion. Acta Otolaryngologica (Stockholm)."},{"key":"S0022215100128828_ref003","first-page":"61","article-title":"An ultrastructural study of the mucosal surface of the human inferior concha. I. Normal appearances","volume":"161","author":"Davis","year":"1988","journal-title":"Journal of Anatomy"},{"key":"S0022215100128828_ref013","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1967.00760050130002"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100128828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T00:35:22Z","timestamp":1557880522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100128828\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,12]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1994,12]]}},"alternative-id":["S0022215100128828"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100128828","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,12]]}}}