{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T06:50:36Z","timestamp":1763967036144},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":4381,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1995,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The alpha-amylase activity in tracheobronchial secretions of 16 consecutive patients with a total laryngectomy was studied. None of these patients had a tracheopharyngeal fistula or pulmonary disorder which might affect the amylase activity. This study proves the presence of amylase in tracheobronchial secretions of laryngectomized patients with a normal lung at a level between x and y and the quantitative analysis of the amylase activity is discussed. The relevance of investigating laryngectomy patients is because of the nature of the surgery the lower respiratory tract is permanently and physically isolated from any other source of salivary amylase. No similar study of the analysis of amylase in normal lung tissue had been reported before.<\/jats:p><jats:p>This information may be of value in order to detect salivary aspiration in patients with a tracheostomy or endotracheal intubation if the level in the aspirate is in the order of a-b times greater than that found in normal tracheobronchial secretions, (x = 35 and y = 1125 i.u.\/l; a = 31.8 and b = 628.6 i.u.\/l).<\/jats:p>","DOI":"10.1017\/s0022215100130890","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:15:19Z","timestamp":1196417719000},"page":"637-639","source":"Crossref","is-referenced-by-count":6,"title":["Amylase activity in tracheobronchial secretions of laryngectomized patients"],"prefix":"10.1017","volume":"109","author":[{"given":"V.","family":"Nandapalan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"McIlwain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"England","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100130890_ref013","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1093\/ajcp\/22.11_ts.1117","article-title":"Simplified laboratory test for acute pancreatitis","volume":"22","author":"Sachar","year":"1952","journal-title":"American Journal of Clinical Pathology"},{"key":"S0022215100130890_ref011","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0022-5223(19)41416-5","article-title":"Serum and urinary amylase levels following pulsatile and continuous cardiopulmonary bypass","volume":"74","author":"Moores","year":"1977","journal-title":"Journal of Thoracic and Cardiovascular Surgery"},{"key":"S0022215100130890_ref003","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.34.7.803"},{"key":"S0022215100130890_ref016","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/21.11.1057"},{"key":"S0022215100130890_ref005","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196109\/10)14:5<1109::AID-CNCR2820140530>3.0.CO;2-X"},{"key":"S0022215100130890_ref004","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196003\/04)13:2<283::AID-CNCR2820130212>3.0.CO;2-2"},{"key":"S0022215100130890_ref010","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195705\/06)10:3<497::AID-CNCR2820100311>3.0.CO;2-7"},{"key":"S0022215100130890_ref015","first-page":"98","article-title":"Influence of organ extracts on the amylolytic action of blood taken from the right and left cardiac halves of rabbits","volume":"28","author":"Takano","year":"1938","journal-title":"Journal of Oriental Medicine, (Abstract Section)"},{"key":"S0022215100130890_ref009","first-page":"2407","article-title":"Die Erhohung des glykolytischen Ferments Diatase in Serum bei Bronchial karzinom als Fruhsymptom","volume":"93","author":"Luhr","year":"1951","journal-title":"Munchener Medizinische Wochenschrift"},{"key":"S0022215100130890_ref006","first-page":"391","volume-title":"Review of Medical Physiology","author":"Ganong","year":"1987"},{"key":"S0022215100130890_ref007","first-page":"155","article-title":"Amylase isoenzyme in a patient with primary bronchial carcinoma","volume":"82","author":"Harada","year":"1971","journal-title":"Medicine and Biology"},{"key":"S0022215100130890_ref012","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0009-8981(77)90240-6","article-title":"The nature and origin of hyperamylasemia following open heart surgery with extracorporeal circulation","volume":"77","author":"Otsuki","year":"1977","journal-title":"Clinica Chimca Ada"},{"key":"S0022215100130890_ref002","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/0016-5085(78)90714-X","article-title":"Amylase changes in disorders of the lung","volume":"74","author":"Berk","year":"1978","journal-title":"Gastroenterology"},{"key":"S0022215100130890_ref001","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/62.6.752"},{"key":"S0022215100130890_ref008","first-page":"17","article-title":"Hyperamylasemia in heroin addicts; characterization by isoamylase analysis","volume":"66","author":"Heffernon","year":"1976","journal-title":"American Journal of Gastroenterology"},{"key":"S0022215100130890_ref014","first-page":"2777","volume":"5","author":"Saugier","year":"1976","journal-title":"Les epanchements riches en amylase en dehors des pancreatities Nouvelle Presse Medicate"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100130890","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T23:54:01Z","timestamp":1588118041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100130890\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1995,7]]}},"alternative-id":["S0022215100130890"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100130890","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,7]]}}}