{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:27:44Z","timestamp":1789475264362,"version":"build-2803163510"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":3953,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1996,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hearing loss was studied in 22 patients with Pierre Robin syndrome (PRS) aged three to 12 years (median 5.0 years). The results were compared to those obtained in 62 patients with isolated cleft palate (ICP) aged one to 27 years (median 5.5 years). Hearing loss was more frequently found in PRS (73.3 per cent) than in ICP (58.1 per cent) patients (<jats:italic>p<\/jats:italic> = 0.02). PRS patients had more ears with moderate (21\u201340 dB) and severe (&gt;40 dB) hearing loss, disturbing their social contact, with no tendency to normalization with age (Spearman r = 0.065). In contrast to PRS, ICP patients showed a significant tendency to hearing level normalization with ageing (Spearman r = \u22120.453; <jats:italic>p<\/jats:italic> = 0.001). Planigraphs of temporal bones showed inadequately developed pneumatization of the mastoid bone in all PRS patients and in most ICP patients. No malformation of the inner or middle ear was found in either group. PRS patients have a significantly higher risk of conductive hearing loss than those with ICP. Use of tympanostomy (ventilation) tubes is therapy of choice in patients with Pierre Robin syndrome, and it should be introduced as early as possible, even at the same time as palatoplasty.<\/jats:p>","DOI":"10.1017\/s0022215100135108","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:14:09Z","timestamp":1196417649000},"page":"830-835","source":"Crossref","is-referenced-by-count":20,"title":["Pierre Robin syndrome: characteristics of hearing loss, effect of age on hearing level and possibilities in therapy planning"],"prefix":"10.1017","volume":"110","author":[{"given":"Jadranka","family":"Hand\u017ei\u0107-\u0106uk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vi\u0161eslav","family":"\u0106uk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranko","family":"Ri\u0161avi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Kati\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damir","family":"Katu\u0161i\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijo","family":"Bagatin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smiljana","family":"\u0160tajner-Katu\u0161i\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damir","family":"Gortan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100135108_ref011","first-page":"1","article-title":"Cleft palate velopharyngeal musculature in five month old infant: three dimensional histological reconstruction","volume":"17","author":"Latham","year":"1980","journal-title":"Cleft Palate Journal"},{"key":"S0022215100135108_ref009","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1970.04310040005002"},{"key":"S0022215100135108_ref013","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-195811000-00003"},{"key":"S0022215100135108_ref001","first-page":"35","volume-title":"Scott-Brown's Otolaryngology","volume":"5","author":"Adams","year":"1987"},{"key":"S0022215100135108_ref010","doi-asserted-by":"publisher","DOI":"10.1007\/BF00455550"},{"key":"S0022215100135108_ref007","first-page":"19","article-title":"Hearing thresholds in cleft lip or palate patients","volume":"19","author":"Hand\u017ei\u0107","year":"1989","journal-title":"Chirurgia Maxillofacialis et Plastica"},{"key":"S0022215100135108_ref006","first-page":"139","volume-title":"The Causes of Profound Deafness in Childhood","author":"Fraser","year":"1976"},{"key":"S0022215100135108_ref004","first-page":"218","article-title":"The anatomy of the auditory tube and paratubal musculature in a one month old cleft palate infant","volume":"20","author":"Doyle","year":"1983","journal-title":"Cleft Palate Journal"},{"key":"S0022215100135108_ref008","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(1995)032<0030:HLIPRS>2.3.CO;2"},{"key":"S0022215100135108_ref015","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100069358"},{"key":"S0022215100135108_ref003","first-page":"587","article-title":"The Robin anomalad \u2013 its nonspecificity and associated syndromes","volume":"34","author":"Cohen","year":"1976","journal-title":"Journal of Oral Surgery"},{"key":"S0022215100135108_ref005","first-page":"131","article-title":"The nasal airway and hearing in patients with cleft palate","volume":"20","author":"Drettner","year":"1952","journal-title":"Acta Otolaryngologica"},{"key":"S0022215100135108_ref002","first-page":"93","article-title":"Roentgenographic evaluation of Eustachian tube in infants with cleft and normal palates","volume":"9","author":"Bluestone","year":"1972","journal-title":"Cleft Palate Journal"},{"key":"S0022215100135108_ref012","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-196005000-00004"},{"key":"S0022215100135108_ref014","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197304000-00009"}],"container-title":["The Journal of Laryngology &amp; 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