{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T17:17:36Z","timestamp":1781111856541,"version":"3.54.1"},"reference-count":7,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":3772,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1997,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A case of sensorineural hearing loss (SNHL) in MELAS syndrome, a variety of mitochondrial cytopathy, is presented. Mitochondrial cytopathies have gone almost unreported in the otolaryngology literature, despite evidence from a recent review that about 60 per cent of such patients suffer from SNHL (Gold and Rapin, 1994). The same review revealed that only one of 117 case reports in the period 1984\u20131993 contained an audiogram (Swift and Singh, 1988), and none presented sequential audiograms. However, audiometry has since been published on 23 members of a family with a mitochondrial point mutation causing only sensorineural hearing loss with no other symptoms (Vernham <jats:italic>et al.<\/jats:italic>, 1994). We present a case of mitochondrial cytopathy three years after diagnosis with two sequential audiograms.<\/jats:p>","DOI":"10.1017\/s0022215100137089","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:13:56Z","timestamp":1196417636000},"page":"279-281","source":"Crossref","is-referenced-by-count":12,"title":["Sensorineural hearing loss in MELAS syndrome"],"prefix":"10.1017","volume":"111","author":[{"given":"P. D.","family":"Warrick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Wardrop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. W.","family":"Sim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100137089_ref007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1994.tb01238.x"},{"key":"S0022215100137089_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100127835"},{"key":"S0022215100137089_ref001","first-page":"717","volume-title":"Diseases of Voluntary Muscle","author":"Bindoff","year":"1994"},{"key":"S0022215100137089_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(87)90212-7"},{"key":"S0022215100137089_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(94)90191-0"},{"key":"S0022215100137089_ref003","first-page":"4171","volume-title":"Oxford Textbook of Medicine","volume":"3","author":"Harding","year":"1996"},{"key":"S0022215100137089_ref006","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100105912"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100137089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T19:05:35Z","timestamp":1557687935000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100137089\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,3]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,3]]}},"alternative-id":["S0022215100137089"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100137089","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,3]]}}}