{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:28:34Z","timestamp":1792056514945,"version":"4.4.0"},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":3346,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1998,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report two patients with Hodgkin's disease on chemotherapy, one with vincristine, the other with vinblastine, who were referred to the ENT department with a vocal fold palsy. These drugs are commonly used in the treatment of haematological malignancies, and head and neck sarcomas. Examination showed a unilateral immobile fold. No causative local pathology was identified, and they were otherwise thought to be achieving remission, but the development of a fold palsy suggested a poor response to treatment. One patient's palsy resolved following completion of chemotherapy, but the other patient's persists, despite an otherwise good response to the treatment. The vinca alkaloids are neurotoxic, usually causing a peripheralneuropathy, but cranial mononeuropathies are a rare side-effect. A total of 27 previous cases of vocal fold palsy have been reported with the use of the vinca alkaloids, and such a lesion should not be assumed to be due to advancing lymphoma.<\/jats:p>","DOI":"10.1017\/s002221510014085x","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T05:13:08Z","timestamp":1196399588000},"page":"485-487","source":"Crossref","is-referenced-by-count":25,"title":["Vocal fold palsy following vinca alkaloid treatment"],"prefix":"10.1017","volume":"112","author":[{"given":"B. V.","family":"Burns","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Shotton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S002221510014085X_ref020","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.38.1.224"},{"key":"S002221510014085X_ref017","doi-asserted-by":"publisher","DOI":"10.1089\/jop.1988.4.117"},{"key":"S002221510014085X_ref016","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-80-6-733"},{"key":"S002221510014085X_ref015","first-page":"787","article-title":"Functional abnormalities invincristine-induced night blindness","volume":"25","author":"Ripps","year":"1984","journal-title":"Investigative Ophthalmology and Visual Science"},{"key":"S002221510014085X_ref011","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810515)47:10<2404::AID-CNCR2820471014>3.0.CO;2-2"},{"key":"S002221510014085X_ref010","doi-asserted-by":"publisher","DOI":"10.1007\/BF01732887"},{"key":"S002221510014085X_ref006","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-197811000-00014"},{"key":"S002221510014085X_ref005","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/96.1.69"},{"key":"S002221510014085X_ref002","first-page":"613","article-title":"Vincristine in the treatment of lymphomas and leukaemias","volume":"23","author":"Bohannon","year":"1963","journal-title":"Cancer Research"},{"key":"S002221510014085X_ref001","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199211000-00011"},{"key":"S002221510014085X_ref004","first-page":"591","article-title":"Vocal fold paralysis: a toxic reaction to vinblastine (NSC-49842) therapy","volume":"55","author":"Brook","year":"1971","journal-title":"Cancer Chemotherapy Reports"},{"key":"S002221510014085X_ref012","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1991.tb00942.x"},{"key":"S002221510014085X_ref009","first-page":"1258","article-title":"Vincristine treatment ofadvanced cancer: a cooperative study of 392 cases","volume":"33","author":"Holland","year":"1973","journal-title":"Cancer Research"},{"key":"S002221510014085X_ref019","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6071.1251"},{"key":"S002221510014085X_ref008","first-page":"116","article-title":"Vincristine and neuropathies","volume":"36","author":"Donaghy","year":"1996","journal-title":"Prescriber's Journal"},{"key":"S002221510014085X_ref018","doi-asserted-by":"publisher","DOI":"10.1007\/BF01713944"},{"key":"S002221510014085X_ref007","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.32.11.1285"},{"key":"S002221510014085X_ref014","doi-asserted-by":"publisher","DOI":"10.1007\/BF01050259"},{"key":"S002221510014085X_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(70)90013-4"},{"key":"S002221510014085X_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(92)90063-V"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S002221510014085X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T16:57:13Z","timestamp":1557507433000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S002221510014085X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,5]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1998,5]]}},"alternative-id":["S002221510014085X"],"URL":"https:\/\/doi.org\/10.1017\/s002221510014085x","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,5]]}}}