{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:25:06Z","timestamp":1787239506683,"version":"build-2736575974"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":3285,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1998,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fifty-five samples of pus were collected from 51 acute, non-perforated, two spontaneously ruptured and two recurrent peritonsillar abscesses (35 males and 18 females; median age 18 years) and analysed regarding (i) aerobic and anaerobic bacteria (standard culturing), (ii) morphology of bacteria and inflammatory cells (direct microscopy of acridine orange-stained material), and (iii) the percentage of bacteria coated with immunoglobulins IgG, secretory IgA (SIgA) andIgM and complement cleavage product C3b (immunofluorescence assay). Seventy-one per cent of the abscesses harboured a mixed bacterial flora of various aerobes and anaerobes. In none of the cases with a single bacterial species (27 per cent) could immunoglobulin- or complement-coated bacteria be found. In abscesses with a mixed flora, 18 per cent harboured IgG-coated, 15 per cent SIgA-coated, five per cent IgM-coated and five per cent C3b-coated bacteria, respectively. All pus samples contained inflammatory cells in abundance but they were mostly deformed and only occasionally could intracellular bacteria be recognized. Insufficient immunoglobulin-coating of bacteria might be an important aetiopathogenic factor in the development of a peritonsillar abscess. Bactericide in the abscesses is accomplished chiefly by protective mechanisms not dependent on antigen recognition by antibodies.<\/jats:p>","DOI":"10.1017\/s0022215100141301","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T05:12:53Z","timestamp":1196399573000},"page":"634-638","source":"Crossref","is-referenced-by-count":5,"title":["Immunoglobulin- and complement-coated bacteria in pus from peritonsillar abscesses"],"prefix":"10.1017","volume":"112","author":[{"given":"Markus","family":"Lilja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simo","family":"R\u00e4is\u00e4nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars-Eric","family":"Stenfors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100141301_ref013","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100133572"},{"key":"S0022215100141301_ref010","first-page":"5.8","volume-title":"Immunology","author":"Rook","year":"1993"},{"key":"S0022215100141301_ref009","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1288\/00005537-199402000-00011","article-title":"Pathogenesis of peritonsillarabscess","volume":"104","author":"Passy","year":"1994","journal-title":"Laryngoscope"},{"key":"S0022215100141301_ref003","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1997.5391899.x"},{"key":"S0022215100141301_ref012","doi-asserted-by":"publisher","DOI":"10.3109\/00016489209100789"},{"key":"S0022215100141301_ref008","doi-asserted-by":"publisher","DOI":"10.1007\/BF01691493"},{"key":"S0022215100141301_ref015","first-page":"12.1","volume-title":"Immunology","author":"Walport","year":"1993"},{"key":"S0022215100141301_ref006","volume-title":"Laboratory outline for training course in principles and bacterial applications of fluorescent antibodies techniques","year":"1972"},{"key":"S0022215100141301_ref014","first-page":"359","volume-title":"Essentials of Medical Microbiology","author":"Volk","year":"1986"},{"key":"S0022215100141301_ref001","doi-asserted-by":"publisher","DOI":"10.1007\/BF02484429"},{"key":"S0022215100141301_ref002","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1288\/00005537-199103000-00012","article-title":"Aerobic and anaerobic microbiology of peritonsillar abscess","volume":"3","author":"Brook","year":"1991","journal-title":"Laryngoscope"},{"key":"S0022215100141301_ref004","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1128\/JCM.26.5.957-961.1988","article-title":"Semiquantitative culture results and pathogenic significance of obligate anaerobes on peritonsillar abscesses","volume":"2","author":"Jokipii","year":"1988","journal-title":"Journal of Clinical Microbiology"},{"key":"S0022215100141301_ref007","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100137429"},{"key":"S0022215100141301_ref011","doi-asserted-by":"publisher","DOI":"10.3109\/00016488909107402"},{"key":"S0022215100141301_ref005","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/16.Supplement_4.S292"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100141301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T16:17:36Z","timestamp":1708359456000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100141301\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1998,7]]}},"alternative-id":["S0022215100141301"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100141301","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,7]]}}}