{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:37:31Z","timestamp":1791171451151,"version":"4.1.0"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T00:00:00Z","timestamp":1183075200000},"content-version":"unspecified","delay-in-days":3162,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[1998,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Forty-five patients with residual or recurrent nasal polyposis after ethmoidectomy were treated with either cetirizine at twice the daily recommended (20 mg) dose or placebo for three months. The number and size of polyps remained unchanged during the study period. Cetirizine was found to reduce nasal sneezing and rhinorrhoea effectively. The drug also had a beneficial effect on nasal obstruction in the latter part of the study. The side effects of 20 mg (double the recommended daily adult dose) of cetirizine were few and comparable to placebo.<\/jats:p>","DOI":"10.1017\/s0022215100142422","type":"journal-article","created":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T10:12:37Z","timestamp":1196417557000},"page":"1042-1046","source":"Crossref","is-referenced-by-count":38,"title":["The effect of cetirizine on symptoms and signs of nasal polyposis"],"prefix":"10.1017","volume":"112","author":[{"given":"Rolf","family":"Haye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens P.","family":"Aanesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Burtin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fergal","family":"Donnelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Duby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,6,29]]},"reference":[{"key":"S0022215100142422_ref014","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100084450"},{"key":"S0022215100142422_ref012","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.12.6.7539273"},{"key":"S0022215100142422_ref002","first-page":"832","article-title":"Histamine, norepinephrine and serotonin content of nasal polyps","volume":"89","author":"Bumstead","year":"1979","journal-title":"Laryngology"},{"key":"S0022215100142422_ref011","first-page":"P","article-title":"Effect of cetirizine on nasal polyps and their associated symptoms","author":"Haye","year":"1995","journal-title":"Allergy"},{"key":"S0022215100142422_ref010","doi-asserted-by":"publisher","DOI":"10.1159\/000237249"},{"key":"S0022215100142422_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90104-8"},{"key":"S0022215100142422_ref001","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1995.tb04259.x"},{"key":"S0022215100142422_ref015","first-page":"60","article-title":"Allergy is not a significant cause of nasal polyps","volume":"21","author":"Slavin","year":"1992","journal-title":"Archives of Otolaryngology"},{"key":"S0022215100142422_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100147462"},{"key":"S0022215100142422_ref006","first-page":"104","article-title":"Antiallergic activity of cetirizme in the treatment of mite allergy in children","author":"Ciprandi","year":"1995","journal-title":"Allergy"},{"key":"S0022215100142422_ref003","first-page":"5","article-title":"Results of oral steroid treatment in nasal polyposis","volume":"32","author":"van Camp","year":"1994","journal-title":"Rhinology"},{"key":"S0022215100142422_ref004","first-page":"41","article-title":"Fine structure of nasal polyps","volume":"81","author":"Cauna","year":"1972","journal-title":"Annals of Otology"},{"key":"S0022215100142422_ref007","first-page":"1","article-title":"Medical treatment of nasal polyps","volume":"32","author":"Drake-Lee","year":"1994","journal-title":"Rhinology"},{"key":"S0022215100142422_ref009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1987.tb02027.x"},{"key":"S0022215100142422_ref013","first-page":"104","article-title":"Surgical versus medical treatment of nasal polyps","volume":"105","author":"Lildholdt","year":"1988","journal-title":"Acta Oto-Laryngologica (Stockh)"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215100142422","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T20:02:20Z","timestamp":1557518540000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215100142422\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1998,11]]}},"alternative-id":["S0022215100142422"],"URL":"https:\/\/doi.org\/10.1017\/s0022215100142422","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,11]]}}}