{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:24:02Z","timestamp":1792653842385,"version":"4.5.0"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2007,9,25]],"date-time":"2007-09-25T00:00:00Z","timestamp":1190678400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215107000473_sec1\">\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>\n                      To describe the incidence trends, clinical presentation, management and outcome of acute epiglottitis in a Danish population after the introduction of\n                      <jats:italic>Haemophilus influenzae<\/jats:italic>\n                      type b vaccine.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215107000473_sec2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective review of the health records of all patients discharged with a diagnosis of acute epiglottitis from the otolaryngology department, Roskilde County Hospital, Denmark, from 1996 to 2005.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215107000473_sec3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      One infant and 34 adults were identified. The incidence of acute epiglottitis in children was 0.02 cases\/100 000\/year. Before introduction of the\n                      <jats:italic>H influenzae<\/jats:italic>\n                      type b vaccination (1983\u20131992), the mean national incidence of acute epiglottitis was 4.9 cases\/100 000\/year. The incidence of acute epiglottitis in adults was constant, with a mean value of 1.9 cases\/100 000\/year. Twenty-nine per cent of the patients required an artificial airway, and respiratory distress was found to be associated with airway intervention (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.010). All patients recovered completely.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215107000473_sec4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      In the\n                      <jats:italic>H influenzae<\/jats:italic>\n                      type b vaccine era, acute epiglottitis in children has almost disappeared. The incidence in the adult population has been constant. A discriminate approach to airway management seems safe in adults.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215107000473","type":"journal-article","created":{"date-parts":[[2007,9,25]],"date-time":"2007-09-25T04:31:31Z","timestamp":1190694691000},"page":"818-823","source":"Crossref","is-referenced-by-count":108,"title":["Acute epiglottitis: epidemiology, clinical presentation, management and outcome"],"prefix":"10.1017","volume":"122","author":[{"given":"L-A","family":"Guldfred","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Lyhne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B C","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,9,25]]},"reference":[{"key":"S0022215107000473_ref23","first-page":"1133","article-title":"Acute epiglottitis in adults. 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