{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T06:27:55Z","timestamp":1784010475000,"version":"3.55.0"},"reference-count":46,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2007,12,19]],"date-time":"2007-12-19T00:00:00Z","timestamp":1198022400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215107001077_sec1\"><jats:title>Aim:<\/jats:title><jats:p>To evaluate hearing changes during \u2018wait and scan\u2019 management of patients with vestibular schwannoma.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107001077_sec2\"><jats:title>Subjects:<\/jats:title><jats:p>Over a 10-year period, 636 patients have prospectively been allocated to \u2018wait and scan\u2019 management, with annual magnetic resonance scanning and audiological examination.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107001077_sec3\"><jats:title>Results:<\/jats:title><jats:p>At the time of diagnosis, 334 patients (53 per cent) had good hearing and speech discrimination of better than 70 per cent; at the end of the 10-year observation period, this latter percentage was 31 per cent. In 17 per cent of the patients, speech discrimination at diagnosis was 100 per cent; of these, 88 per cent still had good hearing at the end of the observation period. However, in patients with even a small initial speech discrimination loss, only 55 per cent maintained good hearing at the end of the observation period.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107001077_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>After comparing the hearing results of hearing preservation surgery and of radiation therapy with those of \u2018wait and scan\u2019 management, it appears that, in vestibular schwannoma patients with a small tumour and normal speech discrimination, the main indication for active treatment should be established tumour growth.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215107001077","type":"journal-article","created":{"date-parts":[[2008,2,11]],"date-time":"2008-02-11T14:38:12Z","timestamp":1202740692000},"page":"673-681","source":"Crossref","is-referenced-by-count":112,"title":["Change in hearing during \u2018wait and scan\u2019 management of patients with vestibular 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