{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:15:32Z","timestamp":1788405332045,"version":"build-2803163510"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2007,5,15]],"date-time":"2007-05-15T00:00:00Z","timestamp":1179187200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215107007256_sec1\"><jats:title>Background:<\/jats:title><jats:p>Acute tonsillitis or pharyngitis may lead to suppurative thrombophlebitis of the internal jugular vein. This complication, also known as Lemierre's syndrome, remains, even nowadays, life threatening, due to dissemination of septic thromboemboli to various organs. Respiratory deficiency and renal impairment are often reported in patients suffering from Lemierre's syndrome.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107007256_sec2\"><jats:title>Case report:<\/jats:title><jats:p>The unusual clinical manifestation of this case involves severe acute renal and respiratory deficiency in addition to microangiopathic consumption coagulopathy in a young patient treated with macrolides five days after the onset of acute tonsillitis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107007256_sec3\"><jats:title>Conclusion:<\/jats:title><jats:p>The usual causative pathogen, namely<jats:italic>Fusobacterium necrophorum<\/jats:italic>, shows a varying sensitivity to macrolides. As a result, the syndrome may present itself in a variety of clinical forms even in patients under treatment with macrolides. A high index of suspicion is therefore crucial for in time prevention of potentially life threatening complications.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215107007256","type":"journal-article","created":{"date-parts":[[2007,5,15]],"date-time":"2007-05-15T09:07:35Z","timestamp":1179220055000},"page":"527-530","source":"Crossref","is-referenced-by-count":5,"title":["Lemierre's syndrome associated with consumption coagulopathy and acute renal failure: a case report"],"prefix":"10.1017","volume":"122","author":[{"given":"S","family":"Georgopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Korres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Riga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Balatsouras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Kotsis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Ferekidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,5,15]]},"reference":[{"key":"S0022215107007256_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198903000-00002"},{"key":"S0022215107007256_ref7","first-page":"41","article-title":"Necrobacillosis","volume":"62","author":"Eykyn","year":"1989","journal-title":"Scand J Infect Dis Suppl"},{"key":"S0022215107007256_ref9","first-page":"384","article-title":"Lemierre syndrome: postanginal sepsis","volume":"8","author":"Leugers","year":"1995","journal-title":"J Am Boar Fam Pract"},{"key":"S0022215107007256_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cppeds.2005.06.002"},{"key":"S0022215107007256_ref6","doi-asserted-by":"crossref","first-page":"S105","DOI":"10.1007\/BF03545601","article-title":"Unusual radiological manifestations of Lemierre's syndrome: a case report","volume":"25","author":"Goyal","year":"1995","journal-title":"Source Pediatr Radiol"},{"key":"S0022215107007256_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(98)00092-5"},{"key":"S0022215107007256_ref5","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1177\/0310057X9802600518","article-title":"Cardiac tamponade in a postpartum woman with Lemierre's syndrome","volume":"26","author":"Mc","year":"1998","journal-title":"Anaesth Intensive Care"},{"key":"S0022215107007256_ref18","first-page":"13","volume-title":"Anaerobic Bacteria in Human Disease","author":"Finegold","year":"1977"},{"key":"S0022215107007256_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100130956"},{"key":"S0022215107007256_ref10","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-51-3-269"},{"key":"S0022215107007256_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0163-4453(91)92684-W"},{"key":"S0022215107007256_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01708619"},{"key":"S0022215107007256_ref17","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.6.1214"},{"key":"S0022215107007256_ref16","first-page":"48","volume-title":"The Sanford Guide to Antimicrobial Therapy, Inc.","author":"Gilbert","year":"1999"},{"key":"S0022215107007256_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S1069-417X(00)89001-9"},{"key":"S0022215107007256_ref12","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00005792-198903000-00002","article-title":"Jugular thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection","volume":"68","author":"DeSena","year":"1989","journal-title":"Medicine"},{"key":"S0022215107007256_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/BF01745348"},{"key":"S0022215107007256_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199610000-00021"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215107007256","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,22]],"date-time":"2020-04-22T01:00:05Z","timestamp":1587517205000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215107007256\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,15]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["S0022215107007256"],"URL":"https:\/\/doi.org\/10.1017\/s0022215107007256","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,15]]}}}