{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T19:02:13Z","timestamp":1791658933195,"version":"4.3.4"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215107007311_sec1\"><jats:title>Objectives:<\/jats:title><jats:p>To identify if there is a link between bacterial colonisation of the tonsillar fossa and post-tonsillectomy haemorrhage.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107007311_sec2\"><jats:title>Study design and setting:<\/jats:title><jats:p>Prospective non-interventional study of 105 patients who underwent tonsillectomy during a seven-month period. The study took place in a secondary care centre, the West Middlesex University Hospital.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107007311_sec3\"><jats:title>Participants:<\/jats:title><jats:p>The participants were 105 patients who consecutively underwent tonsillectomy. The exclusion criteria were any patients with suspected or known malignancy, or known bleeding dyscrasias. The participants underwent microbiological sampling of the tonsil pre-operatively.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107007311_sec4\"><jats:title>Main outcomes measures:<\/jats:title><jats:p>The outcome measures were primary or secondary bleeding, defined as any evidence of haemorrhage in the tonsillar fossae.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107007311_sec5\"><jats:title>Results:<\/jats:title><jats:p>Twenty-four per cent of patients undergoing tonsillectomy had positive cultures from their tonsils pre-operatively. Patients with bacterial colonisation of the tonsillar fossa pre-operatively had an increased rate of post-tonsillectomy haemorrhage (odds ratio: 3.8, 1.1\u201312.1, 95\u00a0per cent confidence intervals,<jats:italic>p<\/jats:italic>\u00a0=\u00a00.04).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215107007311_sec6\"><jats:title>Conclusion:<\/jats:title><jats:p>This prospective study has found a relationship between bacterial colonisation of the tonsillar fossa and post-tonsillectomy haemorrhage. This suggests that there may be an argument for the use of antibiotics in those cases with positive pre-operative cultures. In view of the types of pathogens isolated, we feel that the management of a post-tonsillectomy bleed should include a beta lactamase inhibiting antibiotic.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215107007311","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T07:46:39Z","timestamp":1177055199000},"page":"383-387","source":"Crossref","is-referenced-by-count":17,"title":["Is bacterial colonisation of the tonsillar fossa a factor in post-tonsillectomy haemorrhage?"],"prefix":"10.1017","volume":"122","author":[{"given":"J C","family":"Stephens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Georgalas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Kyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Ghufoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"S0022215107007311_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(06)80182-4"},{"key":"S0022215107007311_ref9","volume-title":"National Prospective Tonsillectomy Audit: Final Report of an audit carried out in England and Northern Ireland between July 2003 and September 2004","year":"2005"},{"key":"S0022215107007311_ref15","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1258\/002221503768199951","article-title":"Bacteraemia during tonsillectomy","volume":"117","author":"Yuldririm","year":"2003","journal-title":"J Laryngol Otol"},{"key":"S0022215107007311_ref7","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1258\/002221503321626429","article-title":"Is the routine use of antibiotics justified in adult tonsillectomy?","volume":"117","author":"O'Reilly","year":"2003","journal-title":"J Laryngol Otol"},{"key":"S0022215107007311_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(96)01364-X"},{"key":"S0022215107007311_ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1986.03780060022002"},{"key":"S0022215107007311_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000163749.77019.8F"},{"key":"S0022215107007311_ref11","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1177\/014556130108000817","article-title":"Evaluation of post tonsillectomy bleeding in the adult population","volume":"80","author":"Bhattacharyya","year":"2001","journal-title":"Ear Nose Throat J"},{"key":"S0022215107007311_ref5","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198903000-00005"},{"key":"S0022215107007311_ref2","first-page":"38","article-title":"Frequency of post tonsillectomy haemorrhage following tonsillectomy with bipolar diathermy- an experience at a teaching hospital, Abbottabad","volume":"16","author":"Shah","year":"2004","journal-title":"Med Coll Abbottabad"},{"key":"S0022215107007311_ref12","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000147942.82626.1c"},{"key":"S0022215107007311_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16896-7"},{"key":"S0022215107007311_ref4","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009901209"},{"key":"S0022215107007311_ref14","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1080\/00016489950182034","article-title":"Tonsillar microbial flora: comparison of recurrent tonsillitis and normal tonsils","volume":"119","author":"Stjernquist-Desatnik","year":"1999","journal-title":"Acta Otolaryngol"},{"key":"S0022215107007311_ref10","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198711000-00011"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215107007311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T13:04:37Z","timestamp":1587474277000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215107007311\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4,20]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0022215107007311"],"URL":"https:\/\/doi.org\/10.1017\/s0022215107007311","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4,20]]}}}