{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T14:41:15Z","timestamp":1707835275786},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A case is presented of a 36-year-old Chinese woman with a renal transplant for end-stage renal failure due to Goodpasture's syndrome. She presented with a year's history of throat discomfort and acid regurgitation into her throat. Videolaryngoscopy revealed bilateral vocal process granuloma, presumed to be due to gastroesophageal reflux. A four-week course of high dose omeprazole was prescribed. On follow up a month later, the granulomas had enlarged, and laser excision was undertaken. Histological and immunohistochemical staining was consistent with Epstein\u2013Barr virus-associated smooth muscle tumour. This is believed to be the first reported case in the English literature of such a tumour affecting the vocal process. The aim of this paper is to present the pathogenesis, clinical behaviour and treatment of Epstein\u2013Barr virus-associated smooth muscle tumour, and to review the literature concerning the differential diagnosis of polypoid vocal process lesions.<\/jats:p>","DOI":"10.1017\/s0022215107007682","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T07:51:26Z","timestamp":1177055486000},"page":"100-104","source":"Crossref","is-referenced-by-count":6,"title":["Epstein\u2013Barr virus-associated smooth muscle tumour mimicking bilateral vocal process granuloma"],"prefix":"10.1017","volume":"122","author":[{"given":"E C","family":"Gan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D P C","family":"Lau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K L","family":"Chuah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"S0022215107007682_ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199501053320112"},{"key":"S0022215107007682_ref9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199501053320103"},{"key":"S0022215107007682_ref12","doi-asserted-by":"publisher","DOI":"10.1177\/000348948509400602"},{"key":"S0022215107007682_ref15","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199902000-00023"},{"key":"S0022215107007682_ref3","doi-asserted-by":"publisher","DOI":"10.1080\/00313020220131309"},{"key":"S0022215107007682_ref8","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1997.86.5.0883"},{"key":"S0022215107007682_ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199501053320104"},{"key":"S0022215107007682_ref14","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10014"},{"key":"S0022215107007682_ref17","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1177\/000348944905800225","article-title":"Contact ulcer granuloma","volume":"58","author":"New","year":"1949","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"S0022215107007682_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63451-7"},{"key":"S0022215107007682_ref2","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000178088.69394.7b"},{"key":"S0022215107007682_ref4","first-page":"127A","article-title":"Post-transplant spindle cell tumor (PTST): an entity associated with Epstein Barr virus","volume":"6","author":"Lee","year":"1993","journal-title":"Mod Pathol"},{"key":"S0022215107007682_ref7","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1128\/JVI.64.5.2309-2318.1990","article-title":"Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3c are effectors in phenotypic changes in B lymphomas: EBNA-2 and LMP1 cooperatively induce CD23","volume":"64","author":"Wang","year":"1990","journal-title":"J Virol"},{"key":"S0022215107007682_ref10","first-page":"834","article-title":"Latent Epstein-Barr virus infection demonstrated in low grade leiomyosarcomas of adults with acquired immunodeficiency syndrome, but not in adjacent Kaposi's lesion or smooth muscle tumors in immunocompetent patients","volume":"121","author":"Boman","year":"1997","journal-title":"Arch Pathol Lab Med"},{"key":"S0022215107007682_ref11","first-page":"277","article-title":"Epstein-Barr virus-associated renal smooth muscle neoplasm: report of a case with review of the literature","volume":"122","author":"Creager","year":"1998","journal-title":"Arch Pathol Lab Med"},{"key":"S0022215107007682_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1960.03020060001001"},{"key":"S0022215107007682_ref16","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199903000-00017"},{"key":"S0022215107007682_ref18","first-page":"825","article-title":"Contact ulcers of the larynx: a reacquaintance with the pathology of an often under-diagnosed entity","volume":"114","author":"Wenig","year":"1990","journal-title":"Arch Pathol Lab Med"},{"key":"S0022215107007682_ref20","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1177\/014556130208101114","article-title":"Bilateral vocal process papillomas: report of a case","volume":"81","author":"Sidle","year":"2002","journal-title":"Ear Nose Throat J"},{"key":"S0022215107007682_ref19","doi-asserted-by":"publisher","DOI":"10.3109\/00016488909127512"}],"container-title":["The Journal of Laryngology &amp; 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