{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T23:59:59Z","timestamp":1771027199827,"version":"3.50.1"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2017,3,8]],"date-time":"2017-03-08T00:00:00Z","timestamp":1488931200000},"content-version":"unspecified","delay-in-days":2868,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215109004496_sec1\"><jats:title>Background:<\/jats:title><jats:p>Congenital cholesteatoma occurring behind the tympanic membrane is typically located in the anterior middle ear.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004496_sec2\"><jats:title>Objective:<\/jats:title><jats:p>To investigate the location, clinical features and treatment of cholesteatomas located behind an intact tympanic membrane in adults.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004496_sec3\"><jats:title>Methods:<\/jats:title><jats:p>Review of a series of 265 consecutive, new, adult cases of previously untreated cholesteatoma seen by the author over a 22-year period.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004496_sec4\"><jats:title>Results:<\/jats:title><jats:p>Seventeen (6 per cent) cases were located behind an intact tympanic membrane without any evidence of a retraction pocket of the attic or pars tensa. Ten (59 per cent) of these patients had undergone previous ear surgery and therefore the disease could reasonably be considered to be iatrogenic. The most common presentation was conductive deafness with no other symptoms (71 per cent). In all of the cases, the disease was located in the posterior half of the middle-ear space. The most common surgical management was simple excision of the disease via a tympanotomy. Two cases (12 per cent) developed residual disease.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004496_sec5\"><jats:title>Conclusion:<\/jats:title><jats:p>The majority of the cases in this series were likely to be acquired cholesteatomas. This type of disease often presents with conductive hearing loss alone.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215109004496","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T04:19:08Z","timestamp":1233721148000},"page":"488-491","source":"Crossref","is-referenced-by-count":12,"title":["Cholesteatoma behind an intact tympanic membrane in adult life: congenital or acquired?"],"prefix":"10.1017","volume":"123","author":[{"given":"R","family":"Mills","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,3,8]]},"reference":[{"key":"S0022215109004496_ref17","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198503000-00005"},{"key":"S0022215109004496_ref12","first-page":"957","article-title":"Congenital and acquired cholesteatoma middle ear in children [Polish]","volume":"58","author":"Kuczkowski","year":"2004","journal-title":"Otolaryngol Pol"},{"key":"S0022215109004496_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2005.02.014"},{"key":"S0022215109004496_ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.7.810"},{"key":"S0022215109004496_ref11","doi-asserted-by":"publisher","DOI":"10.3950\/jibiinkoka.107.998"},{"key":"S0022215109004496_ref5","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1067\/mhn.2002.123446","article-title":"Congenital cholesteatoma: 20 year's experience at the Children's Hospital of Philadelphia","volume":"126","author":"Postic","year":"2002","journal-title":"Otolaryngol Head Neck Surg"},{"key":"S0022215109004496_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(02)00373-7"},{"key":"S0022215109004496_ref3","first-page":"110","volume-title":"Advances in Oto-rhino-laryngology. 40: Pediatric Otology","author":"Tos","year":"1988"},{"key":"S0022215109004496_ref8","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199106000-00006"},{"key":"S0022215109004496_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100100581"},{"key":"S0022215109004496_ref15","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199808000-00016"},{"key":"S0022215109004496_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2005.11.016"},{"key":"S0022215109004496_ref16","first-page":"357","volume":"28","author":"Rappaport","year":"1999","journal-title":"J Otolaryngol"},{"key":"S0022215109004496_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946507400313"},{"key":"S0022215109004496_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-438X(05)82335-7"},{"key":"S0022215109004496_ref14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.1999.00272.x"},{"key":"S0022215109004496_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100115944"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215109004496","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T15:01:15Z","timestamp":1556636475000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215109004496\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S0022215109004496"],"URL":"https:\/\/doi.org\/10.1017\/s0022215109004496","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}