{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T09:23:49Z","timestamp":1769851429489,"version":"3.49.0"},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2009,3,19]],"date-time":"2009-03-19T00:00:00Z","timestamp":1237420800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215109004782_sec1\"><jats:title>Introduction:<\/jats:title><jats:p>Office-based laryngeal injection for the treatment of a variety of voice disorders is an established practice. Various methods of delivery to the vocal folds are in practice.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004782_sec2\"><jats:title>Aim:<\/jats:title><jats:p>We present a simple and repeatable method of injecting botulinum toxin into the larynx.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004782_sec3\"><jats:title>Method:<\/jats:title><jats:p>Botulinum toxin A (Botox<jats:sup>\u00ae<\/jats:sup>) was delivered into the larynx using a channelled fibre-optic laryngoscope under local anaesthetic, in an office setting.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004782_sec4\"><jats:title>Results:<\/jats:title><jats:p>Seven patients received regular botulinum toxin injections, via our preferred method. The treatment intervals and dosage regime varied depending on patient requirements. The procedure was carried out in an office setting, with minimal discomfort and inconvenience to the patient.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109004782_sec5\"><jats:title>Conclusion:<\/jats:title><jats:p>We present a method of botulinum toxin delivery to the larynx which is simple, easily repeatable and simply learnt by the otolaryngologist familiar with fibre-optic laryngoscope usage. This method is also comfortable and convenient for the patient.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215109004782","type":"journal-article","created":{"date-parts":[[2009,3,19]],"date-time":"2009-03-19T10:15:51Z","timestamp":1237457751000},"page":"783-785","source":"Crossref","is-referenced-by-count":7,"title":["Trans-nasal injection of botulinum toxin"],"prefix":"10.1017","volume":"123","author":[{"given":"A","family":"Hussain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Thiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Shakeel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,3,19]]},"reference":[{"key":"S0022215109004782_ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.9.1416"},{"key":"S0022215109004782_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(94)70569-0"},{"key":"S0022215109004782_ref10","doi-asserted-by":"publisher","DOI":"10.1044\/1092-4388(2002\/037)"},{"key":"S0022215109004782_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940010900215"},{"key":"S0022215109004782_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199810000-00030"},{"key":"S0022215109004782_ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1987.01860060029009"},{"key":"S0022215109004782_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/019459989010300515"},{"key":"S0022215109004782_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199707000-00022"},{"key":"S0022215109004782_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01443.x"},{"key":"S0022215109004782_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.4.415"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215109004782","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T12:48:45Z","timestamp":1556628525000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215109004782\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,19]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["S0022215109004782"],"URL":"https:\/\/doi.org\/10.1017\/s0022215109004782","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3,19]]}}}