{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T14:29:57Z","timestamp":1782484197292,"version":"3.54.5"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2009,8,3]],"date-time":"2009-08-03T00:00:00Z","timestamp":1249257600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215109990703_sec1\"><jats:title>Objective:<\/jats:title><jats:p>Inverted papilloma is a rare but locally aggressive tumour with the potential for malignant transformation. Intracranial extension or complications secondary to inverted papilloma are extremely rare. We report a case of inverted papilloma with a large frontal sinus mucocele eroding the frontal sinus, which presented with sudden neurological compromise. A literature review on intracranial extension of such tumours is also included.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109990703_sec2\"><jats:title>Methods:<\/jats:title><jats:p>A Medline search of articles, using the terms \u2018inverted papilloma\u2019, \u2018Ringertz tumour\u2019, \u2018intracranial extension\u2019 and \u2018complication\u2019. Suitable references from the collected articles were also reviewed. Articles published in English were selected and reviewed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109990703_sec3\"><jats:title>Results:<\/jats:title><jats:p>A total of 10 cases was identified. Intracranial spread was more commonly seen in recurrent cases, especially if the recurrence involved the cribriform plate, fovea ethmoidalis or orbits. Cases with extradural disease seemed to have a better prognosis than those with intradural spread.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215109990703_sec4\"><jats:title>Conclusions:<\/jats:title><jats:p>Intracranial involvement of inverted papilloma is extremely rare, and is usually seen in recurrent cases. This case report highlights an unusual but serious case of inverted papilloma presenting with acute neurological deterioration secondary to a large frontal sinus mucocele eroding the frontal sinus. A literature review on intracranial extension of inverted papilloma indicated that common sites of intracranial spread include the cribriform plate, fovea ethmoidalis and orbits. The prognosis for patients with such tumours depends on the type of dural involvement, with intradural extension carrying a poorer prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215109990703","type":"journal-article","created":{"date-parts":[[2009,8,3]],"date-time":"2009-08-03T09:03:25Z","timestamp":1249290205000},"page":"101-104","source":"Crossref","is-referenced-by-count":10,"title":["An unusual presentation of inverted papilloma: case report and literature review"],"prefix":"10.1017","volume":"124","author":[{"given":"V","family":"Visvanathan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Wallace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Chumas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z G G","family":"Makura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,8,3]]},"reference":[{"key":"S0022215109990703_ref1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198911000-00003"},{"key":"S0022215109990703_ref18","first-page":"35","article-title":"Inverted squamous papilloma with neuro-ophthalmic features","volume":"11","author":"Peterson","year":"1991","journal-title":"J Clin Neuroophthalmol"},{"key":"S0022215109990703_ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-004-0818-9"},{"key":"S0022215109990703_ref5","first-page":"139","article-title":"Surgery of inverted papillomas under endoscopic control","volume":"54","author":"Bertrand","year":"2000","journal-title":"Acta Otorhinolaryngol Belg"},{"key":"S0022215109990703_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199609\/10)18:5<450::AID-HED8>3.0.CO;2-4"},{"key":"S0022215109990703_ref20","doi-asserted-by":"publisher","DOI":"10.1002\/lary.5541040513"},{"key":"S0022215109990703_ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00125480-200103000-00001"},{"key":"S0022215109990703_ref9","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199005000-00008"},{"key":"S0022215109990703_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(93)90174-T"},{"key":"S0022215109990703_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100105572"},{"key":"S0022215109990703_ref7","doi-asserted-by":"publisher","DOI":"10.1258\/0022215011908955"},{"key":"S0022215109990703_ref13","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199306000-00003"},{"key":"S0022215109990703_ref23","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200402000-00003"},{"key":"S0022215109990703_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0401-2"},{"key":"S0022215109990703_ref10","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1057117"},{"key":"S0022215109990703_ref21","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200305000-00017"},{"key":"S0022215109990703_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(91)90022-V"},{"key":"S0022215109990703_ref17","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199912)21:8<703::AID-HED4>3.0.CO;2-H"},{"key":"S0022215109990703_ref4","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199503000-00011"},{"key":"S0022215109990703_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.11.038"},{"key":"S0022215109990703_ref6","doi-asserted-by":"publisher","DOI":"10.1177\/000348947108000205"},{"key":"S0022215109990703_ref11","first-page":"E527","article-title":"Frontal sinus mucocoele with intracranial and intraorbital extension","volume":"11","author":"Cagigal","year":"2006","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"S0022215109990703_ref3","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199203000-00001"},{"key":"S0022215109990703_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(95)00165-4"},{"key":"S0022215109990703_ref19","first-page":"539","article-title":"Craniofacial resection for large tumours of the paranasal sinuses","volume":"68","author":"Lewis","year":"1989","journal-title":"Ear Nose Throat J"}],"container-title":["The Journal of Laryngology &amp; 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