{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:20:43Z","timestamp":1761823243698},"reference-count":4,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2010,3,11]],"date-time":"2010-03-11T00:00:00Z","timestamp":1268265600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215110000460_sec1\"><jats:title>Objectives:<\/jats:title><jats:p>To identify the greatest difficulties reported by people affected by neurofibromatosis type 2, and to determine the relationship between the primary and secondary effects of the disease.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110000460_sec2\"><jats:title>Design:<\/jats:title><jats:p>Postal questionnaire study.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110000460_sec3\"><jats:title>Setting:<\/jats:title><jats:p>Questionnaire sent to subjects' home addresses.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110000460_sec4\"><jats:title>Participants:<\/jats:title><jats:p>Eighty-seven adult patients under the care of the Manchester multidisciplinary neurofibromatosis type 2 team were invited to take part.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110000460_sec5\"><jats:title>Main outcome measure:<\/jats:title><jats:p>The response rate was 62 out of 87 (71 per cent).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110000460_sec6\"><jats:title>Results:<\/jats:title><jats:p>Respondents' answers emphasised that their greatest problem was deafness, which resulted in communication difficulties with social contacts, close partners, family and friends. Correlation coefficients indicated a relationship between general mood changes and hearing difficulties, social communication problems, balance difficulties and mobility problems. Self-confidence was significantly related only to social communication problems.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110000460_sec7\"><jats:title>Conclusions:<\/jats:title><jats:p>The use of a closed set neurofibromatosis type 2 questionnaire identified hearing problems and subsequent communication difficulties as the main problems faced by people with this condition.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215110000460","type":"journal-article","created":{"date-parts":[[2010,3,11]],"date-time":"2010-03-11T04:35:17Z","timestamp":1268282117000},"page":"720-728","source":"Crossref","is-referenced-by-count":38,"title":["Use of a closed set questionnaire to measure primary and secondary effects of neurofibromatosis type 2"],"prefix":"10.1017","volume":"124","author":[{"given":"W J","family":"Neary","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V F","family":"Hillier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Flute","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Stephens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R T","family":"Ramsden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D G R","family":"Evans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2010,3,11]]},"reference":[{"key":"S0022215110000460_ref4","unstructured":"4 Neary WJ , Hillier VF , Flute T , Stephens SDG , Ramsden RT , Evans DGR . The relationship between factors identified by the NF2 questionnaire and the domains of the SF-36 questionnaire. Submitted to Clinical Otolaryngology 2009. Revision submitted February 2010."},{"key":"S0022215110000460_ref3","unstructured":"3 Ware JE , Kosinski M . SF-36 Physical and Mental Health Summary Scales: A Manual for Users of Version 1, Second Edition. Lincoln, RI: Quality Metric Incorporated, 2001"},{"key":"S0022215110000460_ref1","doi-asserted-by":"publisher","DOI":"10.1080\/16513860601113825"},{"key":"S0022215110000460_ref2","unstructured":"2 World Health Organization. International Classification of Functioning, Disability and Health (ICF). Geneva: World Health Organization, 2001"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215110000460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,28]],"date-time":"2019-04-28T15:31:56Z","timestamp":1556465516000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215110000460\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,11]]},"references-count":4,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0022215110000460"],"URL":"https:\/\/doi.org\/10.1017\/s0022215110000460","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,11]]}}}