{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T05:46:27Z","timestamp":1791611187344,"version":"4.3.4"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2010,10,26]],"date-time":"2010-10-26T00:00:00Z","timestamp":1288051200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215110002227_sec1\"><jats:title>Objective:<\/jats:title><jats:p>We report a case of cholesterol granuloma of the petrous apex which was surgically treated via an endoscopic trans-sphenoidal approach.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110002227_sec2\"><jats:title>Methods:<\/jats:title><jats:p>Case report and review of the literature concerning cholesterol granulomas of the petrous apex and their management.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110002227_sec3\"><jats:title>Results:<\/jats:title><jats:p>The lesion was approached endoscopically via a bilateral sphenoidotomy with removal of the vomer. A large cholesterol granuloma was evacuated and marsupialised. The patient made an uneventful recovery.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110002227_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>Trans-sphenoidal access to the petrous apex represents an alternative route for the drainage and ventilation of cholesterol granulomas. This approach is the technique of choice when the cholesterol granuloma abuts the posterior wall of the sphenoid sinus. The trans-sphenoid approach, unlike other lateral approaches to the petrous apex, spares cochlear and vestibular function and allows post-operative endoscopic follow up.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215110002227","type":"journal-article","created":{"date-parts":[[2010,10,26]],"date-time":"2010-10-26T10:30:06Z","timestamp":1288089006000},"page":"169-172","source":"Crossref","is-referenced-by-count":10,"title":["Endoscopic trans-sphenoidal removal of cholesterol granuloma of the petrous apex: case report and literature review"],"prefix":"10.1017","volume":"125","author":[{"given":"G","family":"Dhanasekar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N S","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,10,26]]},"reference":[{"key":"S0022215110002227_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(95)90449-2"},{"key":"S0022215110002227_ref20","doi-asserted-by":"publisher","DOI":"10.1177\/000348947708600402"},{"key":"S0022215110002227_ref19","first-page":"793","article-title":"Epidermoid cysts and cholesterol granulomas centered on the posterior fossa: twenty years of diagnosis and management","volume":"21","author":"Sabin","year":"1987","journal-title":"Neurosurgery"},{"key":"S0022215110002227_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100092768"},{"key":"S0022215110002227_ref13","first-page":"28","article-title":"Cholesterol granuloma","volume":"2","author":"Beaumont","year":"1967","journal-title":"J Otolaryngol Aust"},{"key":"S0022215110002227_ref11","doi-asserted-by":"publisher","DOI":"10.1007\/BF01928875"},{"key":"S0022215110002227_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(00)00456-0"},{"key":"S0022215110002227_ref17","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.153.3.6494466"},{"key":"S0022215110002227_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215106009121"},{"key":"S0022215110002227_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2007.01589.x"},{"key":"S0022215110002227_ref5","first-page":"106","article-title":"Endoscopic transrostral-transsphenoidal approach to petrous apex cholesterol granuloma: case report","volume":"19","author":"Samadian","year":"2009","journal-title":"Turk Neurosurg"},{"key":"S0022215110002227_ref4","first-page":"501","article-title":"Surgical anatomy of the transtemporal approaches to the petrous apex","volume":"18","author":"Haberkamp","year":"1997","journal-title":"Am J Otol"},{"key":"S0022215110002227_ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1976.00780110046004"},{"key":"S0022215110002227_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1963.00750020472008"},{"key":"S0022215110002227_ref18","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000303"},{"key":"S0022215110002227_ref24","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.188.3.8351341"},{"key":"S0022215110002227_ref10","first-page":"76","article-title":"Fremdkorperperitonitis with the formation of riesenzellhaltigen Knotchen by encapsulation of cholesterol plaques [in German]","volume":"13","author":"Meyer","year":"1893","journal-title":"Zieglers Beitr"},{"key":"S0022215110002227_ref21","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1058990"},{"key":"S0022215110002227_ref22","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.125.11.1275"},{"key":"S0022215110002227_ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200207000-00023"},{"key":"S0022215110002227_ref12","first-page":"138","article-title":"Crystals and giant cell formation in Mittelohreitenungen [in German]","volume":"16","author":"Wagner","year":"1904","journal-title":"Ver Otol Ges"},{"key":"S0022215110002227_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0015-0"},{"key":"S0022215110002227_ref16","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198909000-00003"},{"key":"S0022215110002227_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200311000-00020"}],"container-title":["The Journal of Laryngology &amp; 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