{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T20:15:22Z","timestamp":1648757722588},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2011,1,27]],"date-time":"2011-01-27T00:00:00Z","timestamp":1296086400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215110002860_sec1\"><jats:title>Objective:<\/jats:title><jats:p>We present the first report in the all English literature of a case of laryngeal squamous cell carcinoma metastasis to the orbit.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110002860_sec2\"><jats:title>Method:<\/jats:title><jats:p>Case report of orbital metastasis from laryngeal carcinoma; clinical, radiological and pathological findings are discussed.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110002860_sec3\"><jats:title>Result:<\/jats:title><jats:p>A 75-year-old man presented to the ENT department with a five-week history of left orbital pain, swelling and reduced vision. Past medical history included laryngectomy, bilateral neck dissection and post-operative radiotherapy for T<jats:sub>4<\/jats:sub> N<jats:sub>2c<\/jats:sub> M<jats:sub>0<\/jats:sub> squamous cell carcinoma of the supraglottis, 10 months earlier. Imaging showed an orbital mass extending along the roof and lateral aspect of the orbit into the optic canal and superior orbital fissure, and further posteriorly into the left cavernous sinus with meningeal enhancement in the left anterior cranial fossa. Histopathological analysis after biopsy showed the mass to be consistent with metastatic poorly differentiated squamous cell carcinoma.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215110002860_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>After searching the all English literature, we report what is, to our best knowledge, the first case of laryngeal carcinoma metastasis to the orbit. Despite its rarity and poor prognosis, such a metastasis should be considered as part of the differential diagnosis of an orbital mass, as timely recognition can improve the patient's quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215110002860","type":"journal-article","created":{"date-parts":[[2011,1,27]],"date-time":"2011-01-27T08:08:20Z","timestamp":1296115700000},"page":"533-535","source":"Crossref","is-referenced-by-count":0,"title":["Laryngeal carcinoma metastasis to the orbit: case report"],"prefix":"10.1017","volume":"125","author":[{"given":"T","family":"Galm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,1,27]]},"reference":[{"key":"S0022215110002860_ref5","doi-asserted-by":"publisher","DOI":"10.1258\/002221503321046757"},{"key":"S0022215110002860_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2008.02.003"},{"key":"S0022215110002860_ref14","first-page":"246","article-title":"Breast carcinoma metastasis to the orbit and paranasal sinuses: a case report","volume":"26","author":"Aspraudis","year":"2004","journal-title":"Exp Oncol"},{"key":"S0022215110002860_ref7","doi-asserted-by":"publisher","DOI":"10.1177\/030089160308900219"},{"key":"S0022215110002860_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200106000-00028"},{"key":"S0022215110002860_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2006.12.004"},{"key":"S0022215110002860_ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.7.762"},{"key":"S0022215110002860_ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000055746"},{"key":"S0022215110002860_ref4","unstructured":"4 Korkmaz H , Dursan E , Saylam G , Akmansu M , Eryilmaz A . An unusual metastatic pattern of larynx cancer: the forearm. KBB-forum 2007 www.KBB-Forum.net"},{"key":"S0022215110002860_ref6","doi-asserted-by":"publisher","DOI":"10.1080\/00016480410024613"},{"key":"S0022215110002860_ref8","first-page":"186","article-title":"Carcinoma of the dura mater. Exophthalmos-Carcinoma of the rectus muscle. General Carcinoma [in German]","volume":"2","author":"Horner","year":"1864","journal-title":"Klin Monartsble Augenheilkd"},{"key":"S0022215110002860_ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000325689"},{"key":"S0022215110002860_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(90)90045-W"},{"key":"S0022215110002860_ref13","first-page":"105","article-title":"A case of prostatic cancer metastatic to the orbit and ethmoid sinus","volume":"584","author":"Saleh","year":"1996","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"S0022215110002860_ref15","first-page":"687","article-title":"Diagnosis and management of orbital metastatic tumors [in Chinese]","volume":"44","author":"Wang","year":"2008","journal-title":"Zhonghua YanKe ZaZhi"},{"key":"S0022215110002860_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197609)38:3<1326::AID-CNCR2820380336>3.0.CO;2-#"},{"key":"S0022215110002860_ref17","doi-asserted-by":"publisher","DOI":"10.1080\/01676830902897470"},{"key":"S0022215110002860_ref18","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.120.3.589"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215110002860","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T04:51:27Z","timestamp":1556340687000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215110002860\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,27]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["S0022215110002860"],"URL":"https:\/\/doi.org\/10.1017\/s0022215110002860","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,27]]}}}