{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:42:53Z","timestamp":1763746973314},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2011,3,4]],"date-time":"2011-03-04T00:00:00Z","timestamp":1299196800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215111000107_sec1\"><jats:title>Objective:<\/jats:title><jats:p>To investigate the hypothesis of cochlear and retrocochlear damage in scrub typhus, using evoked response audiometry.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111000107_sec2\"><jats:title>Study design:<\/jats:title><jats:p>Prospective, randomised, case\u2013control study.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111000107_sec3\"><jats:title>Methods:<\/jats:title><jats:p>The study included 25 patients with scrub typhus and 25 controls with other febrile illnesses not known to cause hearing loss. Controls were age- and sex-matched. All subjects underwent pure tone audiometry and evoked response audiometry before commencing treatment.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111000107_sec4\"><jats:title>Results:<\/jats:title><jats:p>Six patients presented with hearing loss, although a total of 23 patients had evidence of symmetrical high frequency loss on pure tone audiometry. Evoked response audiometry found significant prolongation of absolute latencies of wave I, III, V, and wave I\u2013III interpeak latency. Two cases with normal hearing had increased interpeak latencies. These findings constitute level 3b evidence.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111000107_sec5\"><jats:title>Conclusion:<\/jats:title><jats:p>Findings were suggestive of retrocochlear pathology in two cases with normal hearing. In other patients, high frequency hearing loss may have led to altered evoked response results. Although scrub typhus appears to cause middle ear cochlear and retrocochlear damage, the presence of such damage could not be fully confirmed by evoked response audiometry.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215111000107","type":"journal-article","created":{"date-parts":[[2011,3,4]],"date-time":"2011-03-04T07:13:58Z","timestamp":1299222838000},"page":"567-571","source":"Crossref","is-referenced-by-count":8,"title":["Evoked response audiometry in scrub typhus: prospective, randomised, case\u2013control study"],"prefix":"10.1017","volume":"125","author":[{"given":"J S","family":"Thakur","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N K","family":"Mohindroo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D R","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Soni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S S","family":"Kaushal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,3,4]]},"reference":[{"key":"S0022215111000107_ref16","doi-asserted-by":"publisher","DOI":"10.3109\/01050397909076303"},{"key":"S0022215111000107_ref15","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-198808000-00002"},{"key":"S0022215111000107_ref14","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1978.00790080038010"},{"key":"S0022215111000107_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1977.00780270073012"},{"key":"S0022215111000107_ref12","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1978.00790120035006"},{"key":"S0022215111000107_ref11","first-page":"158","volume-title":"Surgery of the Ear","author":"Stach","year":"2003"},{"key":"S0022215111000107_ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100122832"},{"key":"S0022215111000107_ref6","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2008.4.1.36"},{"key":"S0022215111000107_ref5","doi-asserted-by":"publisher","DOI":"10.1086\/498747"},{"key":"S0022215111000107_ref4","first-page":"512","article-title":"Acute reversible hearing loss in scrub typhus","volume":"55","author":"Mahajan","year":"2007","journal-title":"J Assoc Physician India"},{"key":"S0022215111000107_ref8","doi-asserted-by":"publisher","DOI":"10.1086\/503682"},{"key":"S0022215111000107_ref17","doi-asserted-by":"publisher","DOI":"10.3109\/01050398709042155"},{"key":"S0022215111000107_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.6.1090"},{"key":"S0022215111000107_ref7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-9-173"},{"key":"S0022215111000107_ref3","first-page":"1059","volume-title":"Harrison's Principles of Internal Medicine","author":"Walker","year":"2008"},{"key":"S0022215111000107_ref1","first-page":"629","volume-title":"Oxford Text Book of Medicine","author":"Watt","year":"2003"},{"key":"S0022215111000107_ref2","volume-title":"Mandell, Douglas, Bennett's Principles and Practice of Infectious Diseases","author":"Didier","year":"2010"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215111000107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T04:35:46Z","timestamp":1556339746000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215111000107\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,4]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0022215111000107"],"URL":"https:\/\/doi.org\/10.1017\/s0022215111000107","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,4]]}}}