{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:15:20Z","timestamp":1760955320844},"reference-count":8,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2011,8,22]],"date-time":"2011-08-22T00:00:00Z","timestamp":1313971200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215111001666_sec1\"><jats:title>Objective:<\/jats:title><jats:p>We present a case report and systematic review of acute mastoiditis caused by metastatic lung cancer.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111001666_sec2\"><jats:title>Case report:<\/jats:title><jats:p>A 62-year-old woman developed acute mastoiditis as a complication of otitis media. Cortical mastoidectomy revealed deposits of metastatic non-small cell lung carcinoma around the sigmoid sinus. The patient had previously received treatment for lung cancer, but was thought to be in remission.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111001666_sec3\"><jats:title>Discussion:<\/jats:title><jats:p>A literature review confirmed that this is the first reported case of mastoiditis caused by metastatic lung cancer. Only four similar case reports were identified: two caused by breast carcinoma, one by renal cell carcinoma and one by cholangiocarcinoma. Post-mortem histopathological studies suggest that temporal bone metastasis occurs in 22 per cent of oncology cases.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111001666_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>This is the first reported case of mastoiditis caused by metastatic lung cancer. Metastasis to the temporal bone is not uncommon, but rarely causes mastoiditis.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215111001666","type":"journal-article","created":{"date-parts":[[2011,8,22]],"date-time":"2011-08-22T09:21:42Z","timestamp":1314004902000},"page":"1173-1175","source":"Crossref","is-referenced-by-count":5,"title":["Mastoiditis secondary to metastatic lung carcinoma: case report and literature review"],"prefix":"10.1017","volume":"125","author":[{"given":"P J","family":"Clamp","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A H","family":"Jardine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,8,22]]},"reference":[{"key":"S0022215111001666_ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.2.209"},{"key":"S0022215111001666_ref3","first-page":"587","article-title":"Facial paralysis caused by metastasis of breast carcinoma to the temporal bone","volume":"67","author":"Lan","year":"2004","journal-title":"J Chin Med Assoc"},{"key":"S0022215111001666_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100127914"},{"key":"S0022215111001666_ref1","first-page":"131","article-title":"Cholangiocarcinoma masquerading as mastoiditis","volume":"2","author":"Johnson","year":"1987","journal-title":"Surgical Research Communications"},{"key":"S0022215111001666_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100128208"},{"key":"S0022215111001666_ref8","first-page":"780","article-title":"Metastatic carcinoma of the temporal bone","volume":"17","author":"Streitmann","year":"1996","journal-title":"Am J Otol"},{"key":"S0022215111001666_ref6","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100097784"},{"key":"S0022215111001666_ref4","doi-asserted-by":"publisher","DOI":"10.1177\/014107689809101211"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215111001666","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T04:04:35Z","timestamp":1556337875000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215111001666\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,22]]},"references-count":8,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0022215111001666"],"URL":"https:\/\/doi.org\/10.1017\/s0022215111001666","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,22]]}}}