{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:27:27Z","timestamp":1770978447824,"version":"3.50.1"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2011,8,11]],"date-time":"2011-08-11T00:00:00Z","timestamp":1313020800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215111001812_sec1\"><jats:title>Background:<\/jats:title><jats:p>Thyroid lymphomas are relatively uncommon. This study aimed to analyse our experience of thyroid lymphoma management and outcome.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111001812_sec2\"><jats:title>Materials and methods:<\/jats:title><jats:p>A retrospective case note analysis of 63 patients treated in the previous 13 years was conducted.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111001812_sec3\"><jats:title>Results:<\/jats:title><jats:p>The five-year survival rate was 68 per cent, with most patients dying of their lymphoma. This is at odds with the British Thyroid Association statement that the prognosis of this condition is \u2018generally excellent\u2019. The only presenting symptom found to be significantly associated with prognosis was dysphagia (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001). Dual modality treatment provided a significantly better outcome than single modality treatment (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.014). Thyroid lymphoma can present to the head and neck surgeon \u2018in extremis\u2019; however, it can respond rapidly to appropriate treatment.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111001812_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>The outcome of thyroid lymphoma seems unrelated to the acuteness of its presentation. Thyroid surgery has no role other than for diagnosis. However, 51 per cent of the study patients underwent some form of thyroidectomy, indicating the need to implement better diagnostic pathways.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215111001812","type":"journal-article","created":{"date-parts":[[2011,8,11]],"date-time":"2011-08-11T14:29:54Z","timestamp":1313072994000},"page":"1256-1262","source":"Crossref","is-referenced-by-count":6,"title":["Thyroid lymphoma: acute presentation and long-term outcome"],"prefix":"10.1017","volume":"125","author":[{"given":"S E","family":"Penney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J J","family":"Homer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,8,11]]},"reference":[{"key":"S0022215111001812_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/BF02557529"},{"key":"S0022215111001812_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0936-6555(05)80271-7"},{"key":"S0022215111001812_ref10","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1993.3.93"},{"key":"S0022215111001812_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(92)90790-O"},{"key":"S0022215111001812_ref4","first-page":"89","article-title":"Primary lymphoma of the thyroid, the association with Hashimoto's thyroiditis","volume":"18","author":"Scholefield","year":"1992","journal-title":"Eur J Surg Oncol"},{"key":"S0022215111001812_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s002680010159"},{"key":"S0022215111001812_ref12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198503073121001"},{"key":"S0022215111001812_ref9","volume-title":"Guidelines for the management of thyroid cancer","author":"Perros","year":"2007"},{"key":"S0022215111001812_ref7","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-200106000-00019"},{"key":"S0022215111001812_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-004-0021-7"},{"key":"S0022215111001812_ref6","first-page":"316","article-title":"Primary thyroid lymphoma","volume":"26","author":"Ansell","year":"1999","journal-title":"Semin Oncol"},{"key":"S0022215111001812_ref14","doi-asserted-by":"publisher","DOI":"10.2165\/00063030-200620040-00006"},{"key":"S0022215111001812_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19940101)73:1<200::AID-CNCR2820730135>3.0.CO;2-#"},{"key":"S0022215111001812_ref1","first-page":"225","volume-title":"Oxford Textbook of Medicine","volume":"3","author":"Weetman","year":"2003"},{"key":"S0022215111001812_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/01.coc.0000054891.30422.B5"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215111001812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T03:13:58Z","timestamp":1556334838000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215111001812\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,11]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0022215111001812"],"URL":"https:\/\/doi.org\/10.1017\/s0022215111001812","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,11]]}}}