{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:48:26Z","timestamp":1790171306143,"version":"4.1.0"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2011,9,14]],"date-time":"2011-09-14T00:00:00Z","timestamp":1315958400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215111002209_sec1\"><jats:title>Background:<\/jats:title><jats:p>Wegener's granulomatosis is a rare but well recognised autoimmune necrotising vasculitis. Presentation of disease in the head and neck is common and mostly consists of nasal crusting, blockage and bloody discharge. Neurological presentation is very uncommon.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111002209_sec2\"><jats:title>Methods:<\/jats:title><jats:p>We report a patient who presented to the medical emergency services with signs and symptoms of meningitis, but who was eventually diagnosed with Wegener's granulomatosis. A literature search on this topic was carried out using Medline and Embase (1996 to 2011), searching for \u2018Wegener's granulomatosis\u2019 and \u2018meningitis\u2019.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111002209_sec3\"><jats:title>Results:<\/jats:title><jats:p>After thorough neurological and medical investigation, a combination of brain computed tomography, lumbar puncture, nasal biopsy and laboratory results refuted the diagnosis of meningitis and confirmed the diagnosis of Wegener's granulomatosis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111002209_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>To the best of our knowledge, this is the first English-language case report of a patient with Wegener's granulomatosis presenting with symptoms of meningitis unconfirmed on computed tomography and lumbar puncture.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215111002209","type":"journal-article","created":{"date-parts":[[2011,9,14]],"date-time":"2011-09-14T07:33:58Z","timestamp":1315985638000},"page":"207-209","source":"Crossref","is-referenced-by-count":2,"title":["Wegener's granulomatosis presenting as meningitis"],"prefix":"10.1017","volume":"126","author":[{"given":"G","family":"Thiel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Shakeel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Ah-See","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2011,9,14]]},"reference":[{"key":"S0022215111002209_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200101000-00008"},{"key":"S0022215111002209_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00059-004-2525-0"},{"key":"S0022215111002209_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200005)43:5<1021::AID-ANR10>3.0.CO;2-J"},{"key":"S0022215111002209_ref5","first-page":"202","article-title":"Of generalized septic vessel disease [in German]","volume":"29","author":"Wegener","year":"1936","journal-title":"Verh Dtsch Ges Pathol"},{"key":"S0022215111002209_ref1","first-page":"227","article-title":"Head and neck manifestations of Wegener's granulomatosis","volume":"44","author":"Gottschlich","year":"2006","journal-title":"Rhinology"},{"key":"S0022215111002209_ref3","first-page":"S60","article-title":"Meningeal involvement in Wegener's granulomatosis is associated with localized disease","volume":"2","author":"Di Comite","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"S0022215111002209_ref7","doi-asserted-by":"publisher","DOI":"10.1002\/art.20928"},{"key":"S0022215111002209_ref10","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-98-1-76"},{"key":"S0022215111002209_ref4","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1002\/art.11075","article-title":"Limited versus severe Wegener's granulomatosis: baseline data on patients in the Wegener's granulomatosis Etanercept trial","volume":"48","author":"Stone","year":"2003","journal-title":"Arthritis Rheum"},{"key":"S0022215111002209_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199006000-00006"},{"key":"S0022215111002209_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/39.12.1396"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215111002209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T21:53:51Z","timestamp":1556229231000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215111002209\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,14]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0022215111002209"],"URL":"https:\/\/doi.org\/10.1017\/s0022215111002209","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,14]]}}}