{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T10:34:00Z","timestamp":1648982040175},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2011,10,10]],"date-time":"2011-10-10T00:00:00Z","timestamp":1318204800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215111002672_sec1\"><jats:title>Objective:<\/jats:title><jats:p>A 33-year-old woman presented with a three-day history of an abscess in the left alar region, four weeks after drainage of a breast abscess. The later infection was confirmed to be due to Panton\u2013Valentine leukocidin positive, methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic>. This report aims to raise awareness of such infections, and to advise when Panton\u2013Valentine leukocidin toxin testing is appropriate.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111002672_sec2\"><jats:title>Method:<\/jats:title><jats:p>Case report and discussion.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111002672_sec3\"><jats:title>Results:<\/jats:title><jats:p>Although superficial Panton\u2013Valentine leukocidin positive <jats:italic>Staphylococcus aureus<\/jats:italic> infections are relatively benign, more serious infections can be potentially life-threatening. Clinicians should be able to identify the features of potential Panton\u2013Valentine leukocidin positive <jats:italic>Staphylococcus aureus<\/jats:italic> infection, in order to implement appropriate therapy.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215111002672_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>Clinicians need to be aware of Panton\u2013Valentine leukocidin positive <jats:italic>Staphylococcus aureus<\/jats:italic> infections, and should ask specific questions when investigating the clinical history of patients with recurrent abscesses, as this bacterial strain is not routinely assessed by microbiology departments. If such an infection is suspected, clinicians should be aware of local protocols regarding toxin testing, antibiotic choice and decolonisation agents.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215111002672","type":"journal-article","created":{"date-parts":[[2011,10,10]],"date-time":"2011-10-10T16:04:02Z","timestamp":1318262642000},"page":"325-327","source":"Crossref","is-referenced-by-count":0,"title":["More than just a simple abscess: could it be caused by Panton\u2013Valentine leukocidin positive <i>Staphylococcus aureus<\/i>?"],"prefix":"10.1017","volume":"126","author":[{"given":"J","family":"Manara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Shears","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,10,10]]},"reference":[{"key":"S0022215111002672_ref6","volume-title":"Interim Guidance on Diagnosis and Management of PVL-associated Staphylococcal Infections in the UK","author":"McCartney"},{"key":"S0022215111002672_ref1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.5.2384-2390.2005"},{"key":"S0022215111002672_ref2","first-page":"170","article-title":"Necrotising pneumonia, Staphylococcus aureus and Panton-Valentine leukocidin","volume":"9","author":"McGrath","year":"2008","journal-title":"JICS"},{"key":"S0022215111002672_ref3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.331.7520.793"},{"key":"S0022215111002672_ref9","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.3.1141-1144.2006"},{"key":"S0022215111002672_ref5","first-page":"1","article-title":"PVL-SA infections in England and Wales: 2005\u20132008 data and revised algorithm for referral of suspected cases","volume":"3","author":"Anonymous","year":"2009","journal-title":"Health Protection Agency News Archives"},{"key":"S0022215111002672_ref7","first-page":"12","article-title":"Guidance on the diagnosis and management of PVL-associated Staphylococcus aureus infections (PVL-SA) in England","volume":"2","author":"Anonymous","year":"2008","journal-title":"HPA"},{"key":"S0022215111002672_ref4","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.061370"},{"key":"S0022215111002672_ref8","doi-asserted-by":"publisher","DOI":"10.1592\/phco.23.5.638.32191"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215111002672","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T01:26:11Z","timestamp":1556241971000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215111002672\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,10]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0022215111002672"],"URL":"https:\/\/doi.org\/10.1017\/s0022215111002672","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,10]]}}}