{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T03:16:39Z","timestamp":1778037399086,"version":"3.51.4"},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2011,11,4]],"date-time":"2011-11-04T00:00:00Z","timestamp":1320364800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,3]]},"abstract":"Abstract<\/jats:title>Objective:<\/jats:title>To demonstrate that patients who have been intubated for prolonged periods of time will have an increased likelihood of developing bacterial biofilm on their endotracheal tubes.<\/jats:p><\/jats:sec>Methods:<\/jats:title>We collected endotracheal tubes from patients at the time of extubation, and analysed representative sections with scanning electron microscopy for morphologic evidence of biofilms.<\/jats:p><\/jats:sec>Results:<\/jats:title>From September 2007 to September 2008, 32 endotracheal tubes were analysed with electron microscopy. Patients who had been intubated for 6 days or longer had a significantly higher percentage of endotracheal tubes that exhibited bacterial biofilms, compared with patients intubated for less than 6 days (88.9 versus 57.1 per cent,p<\/jats:italic>\u00a0=\u00a00.0439).<\/jats:p><\/jats:sec>Conclusions:<\/jats:title>Longer duration of intubation is associated with a higher incidence of bacterial biofilm. Further research is needed to link the presence of bacterial biofilms to acquired laryngotracheal damage.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215111002969","type":"journal-article","created":{"date-parts":[[2011,11,4]],"date-time":"2011-11-04T10:19:04Z","timestamp":1320401944000},"page":"267-270","source":"Crossref","is-referenced-by-count":15,"title":["Biofilm accumulation on endotracheal tubes following prolonged intubation"],"prefix":"10.1017","volume":"126","author":[{"given":"J M","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Hashmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J D","family":"Bloom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Tamashiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Doghramji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Sarani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J N","family":"Palmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N A","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Mirza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,11,4]]},"reference":[{"key":"S0022215111002969_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1995.tb01601.x"},{"key":"S0022215111002969_ref10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2000.00422-13.x"},{"key":"S0022215111002969_ref9","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.2.167-193.2002"},{"key":"S0022215111002969_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31816073e3"},{"key":"S0022215111002969_ref7","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1177\/014556130208100915","article-title":"Biofilm formation on tracheostomy tubes","volume":"81","author":"Jarrett","year":"2002","journal-title":"Ear Nose Throat J"},{"key":"S0022215111002969_ref6","first-page":"46","article-title":"Recurring and antimicrobial-resistant infections: considering the potential role of biofilms in clinical practice","volume":"53","author":"Saye","year":"2007","journal-title":"Ostomy Wound Manage"},{"key":"S0022215111002969_ref4","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s002480000057","article-title":"Spatial organization of microbial biofilm communities","volume":"40","author":"Tolker-Nielsen","year":"2000","journal-title":"Microb Ecol"},{"key":"S0022215111002969_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s001340051014"},{"key":"S0022215111002969_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940711600308"},{"key":"S0022215111002969_ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.300.7.805"},{"key":"S0022215111002969_ref2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.96.1.178"},{"key":"S0022215111002969_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20249"}],"container-title":["The Journal of Laryngology & Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215111002969","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T02:32:36Z","timestamp":1593225156000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215111002969\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,4]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0022215111002969"],"URL":"https:\/\/doi.org\/10.1017\/s0022215111002969","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,4]]}}}