{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T16:10:22Z","timestamp":1772122222801,"version":"3.50.1"},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2012,1,4]],"date-time":"2012-01-04T00:00:00Z","timestamp":1325635200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0022215111003215_sec1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>There is wide variation in UK prescribing practice regarding prophylactic antibiotics for nasal packing in spontaneous epistaxis. There are few published cases of infective complications in such patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215111003215_sec2\">\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>This prospective study examined 149 consecutive patients admitted to a tertiary otorhinolaryngology centre with spontaneous epistaxis, who underwent nasal packing, over a six-month period. In the first three-month period, 78 patients were routinely prescribed prophylactic antibiotics; in the second three months, 71 patients were not routinely prescribed antibiotics. Exclusion criteria included antibiotics prescribed for unrelated pathology and post-operative epistaxis. Signs and symptoms of acute otitis media, sinusitis and toxic shock syndrome were assessed using clinical examination and a questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215111003215_sec3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fourteen of the 149 patients experienced otalgia, most commonly following posterior nasal packing. No patient in either group had evidence of any infective complication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0022215111003215_sec4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We do not recommend the routine prescription of prophylactic antibiotics for patients undergoing nasal packing for spontaneous epistaxis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0022215111003215","type":"journal-article","created":{"date-parts":[[2012,1,4]],"date-time":"2012-01-04T11:58:12Z","timestamp":1325678292000},"page":"257-259","source":"Crossref","is-referenced-by-count":31,"title":["Prospective study of the risk of not using prophylactic antibiotics in nasal packing for epistaxis"],"prefix":"10.1017","volume":"126","author":[{"given":"C","family":"Pepper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Lo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Toma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,1,4]]},"reference":[{"key":"S0022215111003215_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2008.01795.x"},{"key":"S0022215111003215_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100116548"},{"key":"S0022215111003215_ref8","doi-asserted-by":"publisher","DOI":"10.1148\/118.2.351"},{"key":"S0022215111003215_ref3","doi-asserted-by":"publisher","DOI":"10.1201\/b15118-141"},{"key":"S0022215111003215_ref5","volume-title":"Clinical Otology and Audiology","author":"Browning","year":"1998"},{"key":"S0022215111003215_ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1977.00780260051004"},{"key":"S0022215111003215_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(88)90147-7"},{"key":"S0022215111003215_ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2006.01336.x"},{"key":"S0022215111003215_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200409000-00007"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215111003215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T21:26:08Z","timestamp":1556227568000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215111003215\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,4]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0022215111003215"],"URL":"https:\/\/doi.org\/10.1017\/s0022215111003215","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.14260956.15779627","asserted-by":"object"}]},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,4]]}}}