{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T00:05:38Z","timestamp":1794269138064,"version":"4.9.0"},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2012,4,12]],"date-time":"2012-04-12T00:00:00Z","timestamp":1334188800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215112000539_sec1\"><jats:title>Introduction:<\/jats:title><jats:p>Meningiomas are slow-growing, benign tumours originating from the arachnoid villi of the meninges. They account for 13 to 26 per cent of all intracranial neoplasms. Less than 1 per cent of all meningiomas are primary extracranial tumours of the ear and temporal bone. Intracranial meningiomas extending to the middle-ear cleft are uncommon, with fewer than 100 cases reported to date. Presenting symptoms of the latter condition may include hearing loss, tinnitus, dizziness, vertigo and facial palsy. Otitis media with effusion secondary to eustachian tube dysfunction has also been reported.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215112000539_sec2\"><jats:title>Aim:<\/jats:title><jats:p>To describe three patients in whom chronic otitis media was the presenting sign of skull base meningioma.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215112000539_sec3\"><jats:title>Method:<\/jats:title><jats:p>Case presentations.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215112000539_sec4\"><jats:title>Results:<\/jats:title><jats:p>Presentation of clinical and imaging findings as well as management considerations.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215112000539_sec5\"><jats:title>Conclusion:<\/jats:title><jats:p>Meningioma involving the middle ear is an extremely rare condition, and is diagnosed by computed tomography in conjunction with magnetic resonance imaging. When biopsy is performed, the histological features, characteristic immunophenotype and ultrastructural analysis are valuable aids to definitive diagnosis. In patients with no neurological symptoms, \u2018wait and scan\u2019 is often the best management option.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215112000539","type":"journal-article","created":{"date-parts":[[2012,4,12]],"date-time":"2012-04-12T04:03:59Z","timestamp":1334203439000},"page":"619-624","source":"Crossref","is-referenced-by-count":12,"title":["Skull base meningiomas mimicking otitis media"],"prefix":"10.1017","volume":"126","author":[{"given":"R","family":"Shihada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Lurie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Luntz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2012,4,12]]},"reference":[{"key":"S0022215112000539_ref10","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2006.105.4.538"},{"key":"S0022215112000539_ref7","first-page":"329","volume-title":"Merritt's Textbook of Neurology","author":"Rowland","year":"1995"},{"key":"S0022215112000539_ref5","first-page":"544","article-title":"Meningioma extending into the middle ear mimicking chronic otitis media","volume":"10","author":"Khalaila","year":"2008","journal-title":"Isr Med Assoc J"},{"key":"S0022215112000539_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(98)70030-0"},{"key":"S0022215112000539_ref9","doi-asserted-by":"publisher","DOI":"10.3171\/FOC\/2008\/24\/5\/E2"},{"key":"S0022215112000539_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02943181"},{"key":"S0022215112000539_ref2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000227904.55107.ec"},{"key":"S0022215112000539_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16153-9"},{"key":"S0022215112000539_ref4","first-page":"403","article-title":"Temporal meningiomas presenting as chronic otitis media","volume":"14","author":"Civantos","year":"1993","journal-title":"Am J Otol"},{"key":"S0022215112000539_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2008.01.010"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215112000539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T17:27:42Z","timestamp":1556213262000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215112000539\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,12]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0022215112000539"],"URL":"https:\/\/doi.org\/10.1017\/s0022215112000539","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,12]]}}}