{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T01:29:21Z","timestamp":1721006961634},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T00:00:00Z","timestamp":1343088000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>We present the first report of a case of neuroendocrine carcinoma of the paranasal sinuses treated successfully with radiotherapy alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p>A case report and literature review are presented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Fewer than 50 cases of paranasal sinus neuroendocrine carcinoma have been reported. We present an 82-year-old man referred with recurrent epistaxis. He was investigated by biopsy, computed tomography and magnetic resonance imaging, and was found to have a rare neuroendocrine carcinoma. He declined any surgery or chemotherapy but consented to radiotherapy. Thirty months later, he remained clinically free from cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>There is no consensus for the management of paranasal sinus neuroendocrine carcinoma. Most cases are treated with surgery with or without chemoradiotherapy. This case shows that radiotherapy alone may be a viable treatment option for some cases.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215112001600","type":"journal-article","created":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T03:20:36Z","timestamp":1343100036000},"page":"1066-1068","source":"Crossref","is-referenced-by-count":3,"title":["Neuroendocrine carcinoma of the ethmoid sinuses treated with radiotherapy alone"],"prefix":"10.1017","volume":"126","author":[{"given":"P W","family":"Flavahan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Keir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,7,24]]},"reference":[{"key":"S0022215112001600_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10345"},{"key":"S0022215112001600_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(01)00558-7"},{"key":"S0022215112001600_ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.03.078"},{"key":"S0022215112001600_ref2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19821201)50:11<2388::AID-CNCR2820501126>3.0.CO;2-K"},{"key":"S0022215112001600_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S1607-551X(09)70054-3"},{"key":"S0022215112001600_ref11","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1177\/014556130808700511","article-title":"Sinonasal neuroendocrine carcinoma: a case report","volume":"87","author":"Mendis","year":"2008","journal-title":"Ear Nose Throat J"},{"key":"S0022215112001600_ref9","first-page":"E1","article-title":"Small-cell neuroendocrine carcinoma originating from the lateral nasopharyngeal wall","volume":"87","author":"Deviprasad","year":"2008","journal-title":"Ear Nose Throat J"},{"key":"S0022215112001600_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2006.09.014"},{"key":"S0022215112001600_ref8","first-page":"41","article-title":"Poorly differentiated neuroendocrine carcinoma of the nasal cavity","volume":"14","author":"Lin","year":"2009","journal-title":"Mid-Taiwan Journal of Medicine"},{"key":"S0022215112001600_ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215106000594"},{"key":"S0022215112001600_ref1","first-page":"59","article-title":"Sinonasal tumours: paraganglioma, nasal polyps, frontal sinus mucocele; diagnosis, therapy, prognosis \u2013 a case report","volume":"32","author":"Grabovac","year":"2004","journal-title":"Libri Oncologici"},{"key":"S0022215112001600_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2007.12.005"},{"key":"S0022215112001600_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3181671491"},{"key":"S0022215112001600_ref4","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.053314"},{"key":"S0022215112001600_ref14","first-page":"147","article-title":"A neuroendocrine tumour of the sphenoid sinus and nasopharynx: a case report","volume":"6","author":"Vandist","year":"2010","journal-title":"B-ENT"},{"key":"S0022215112001600_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2007.02.010"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215112001600","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T12:07:43Z","timestamp":1561982863000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215112001600\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,24]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0022215112001600"],"URL":"https:\/\/doi.org\/10.1017\/s0022215112001600","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,24]]}}}