{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T17:53:12Z","timestamp":1680285192352},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T00:00:00Z","timestamp":1346716800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>To discuss the minimally invasive treatment and prognosis of juvenile nasopharyngeal angiofibroma involving the eye and optic nerve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Retrospective analysis of clinical data for 18 large juvenile nasopharyngeal angiofibromas, with reports of three typical cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The tumour invaded the orbit, eye, optic nerve and optic chiasm in 18, 9, 8 and 5 patients, respectively. Twelve patients were cured after surgery, with the affected eye and vision essentially returning to normal. In six patients, tumour residue was found in the middle cranial fossa; two of these six did not return for follow up. Four patients underwent radiotherapy; all four regained placement of the eye in a normal or near-normal position. One of these four patients regained normal visual acuity, two experienced no improvement in visual acuity, and one became blind.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>In patients with this tumour, surgery may return the eye to the normal position and may restore visual acuity if the optic fundus, macula, retina and optic nerve are only mildly affected. Modern radiotherapy can treat the intracranial residue effectively. A combined approach via the antrum, infratemporal fossa and nasal cavity, using a Caldwell\u2013Luc incision, provides minimally invasive surgical access.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215112001831","type":"journal-article","created":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T08:59:24Z","timestamp":1346749164000},"page":"1108-1113","source":"Crossref","is-referenced-by-count":3,"title":["Treatment and prognosis of nasopharyngeal angiofibroma involving the eye and optic nerve"],"prefix":"10.1017","volume":"126","author":[{"given":"Y","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Lan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,9,4]]},"reference":[{"key":"S0022215112001831_ref8","doi-asserted-by":"crossref","first-page":"211","DOI":"10.2310\/7070.2003.41526","article-title":"Huge lobulated juvenile angiofibroma: sites of extension and selection of procedures for management","volume":"32","author":"Yi","year":"2003","journal-title":"J Otolaryngol"},{"key":"S0022215112001831_ref11","first-page":"427","article-title":"Modern radiation treatment of nasopharyngeal angiofibroma of postoperative residual","volume":"45","author":"Yi","year":"2010","journal-title":"Chin J Otorhinolaryngol Head Neck Surg"},{"key":"S0022215112001831_ref10","first-page":"763","article-title":"Pathological features and clinical management of nasopharyngeal angiofibroma [in Chinese]","volume":"43","author":"Lin","year":"2008","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"S0022215112001831_ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890140012004"},{"key":"S0022215112001831_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/01.IOP.0000132163.00869.44"},{"key":"S0022215112001831_ref2","first-page":"560","article-title":"Ocular findings in juvenile nasopharyngeal angiofibroma","volume":"17","author":"Stern","year":"1986","journal-title":"Ophthal Surg"},{"key":"S0022215112001831_ref6","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.105061"},{"key":"S0022215112001831_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(89)32661-3"},{"key":"S0022215112001831_ref7","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21337"},{"key":"S0022215112001831_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2003.12.003"},{"key":"S0022215112001831_ref9","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215107005737"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215112001831","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T17:58:28Z","timestamp":1556128708000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215112001831\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,4]]},"references-count":11,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0022215112001831"],"URL":"https:\/\/doi.org\/10.1017\/s0022215112001831","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,4]]}}}