{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T14:41:10Z","timestamp":1772030470858,"version":"3.50.1"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2012,9,19]],"date-time":"2012-09-19T00:00:00Z","timestamp":1348012800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>Several studies have reported the use of peritonsillar infiltrations of local anaesthetics and\/or locally active analgesic drugs for the relief of post-tonsillectomy pain, with variable results in terms of quality and duration of analgesia. We aimed to compare the effects of peritonsillar infiltration of lidocaine versus tramadol versus placebo on post-tonsillectomy pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Sixty patients over the age of 10 years undergoing bilateral elective tonsillectomy under general anaesthesia were randomised into three groups. The first group received peritonsillar infiltration of tramadol, the second 2 per cent lidocaine and the third normal saline. In all groups, peritonsillar infiltration was carried out after tonsillectomy but prior to tracheal extubation. Post-operative comparisons were made to assess the quality of pain control and the patients' analgesic requirements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Peritonsillar infiltration of tramadol provided an analgesic effect comparable to that of lidocaine in the first 6 hours post-operation, as reflected by visual analogue scale pain scores and opioid requirements, which were lower compared with the placebo group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Peritonsillar infiltration of tramadol provided pain control in the first 6 hours post-tonsillectomy which was comparable to that of lidocaine.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215112002058","type":"journal-article","created":{"date-parts":[[2012,9,19]],"date-time":"2012-09-19T08:49:09Z","timestamp":1348044549000},"page":"1138-1141","source":"Crossref","is-referenced-by-count":23,"title":["Comparison of peritonsillar infiltration of tramadol and lidocaine for the relief of post-tonsillectomy pain"],"prefix":"10.1017","volume":"126","author":[{"given":"M H","family":"Heiba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Atef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Mosleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"El-Hamamsy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,9,19]]},"reference":[{"key":"S0022215112002058_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.11.002"},{"key":"S0022215112002058_ref5","first-page":"251","article-title":"Effects of irradiation on post-tonsillectomy pain","volume":"71","author":"Hope","year":"1954","journal-title":"Am J Roentgenol Radium Ther Nucl Med"},{"key":"S0022215112002058_ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1991.01870180085016"},{"key":"S0022215112002058_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(00)82008-X"},{"key":"S0022215112002058_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.4.385"},{"key":"S0022215112002058_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0479-6"},{"key":"S0022215112002058_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(85)90145-9"},{"key":"S0022215112002058_ref7","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/79.3.352"},{"key":"S0022215112002058_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/BF03006321"},{"key":"S0022215112002058_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e32831c8988"},{"key":"S0022215112002058_ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199911000-00042"},{"key":"S0022215112002058_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-010-0978-2"},{"key":"S0022215112002058_ref17","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1177\/0310057X0002800403","article-title":"Tramadol: present and future","volume":"28","author":"Shipton","year":"2000","journal-title":"Anesth Intensive Care"},{"key":"S0022215112002058_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(02)01368-7"},{"key":"S0022215112002058_ref12","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000135640.21229.A0"},{"key":"S0022215112002058_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeg079"},{"key":"S0022215112002058_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198909001-00694"},{"key":"S0022215112002058_ref8","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000049683.58980.30"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215112002058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T21:58:31Z","timestamp":1556143111000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215112002058\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,19]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0022215112002058"],"URL":"https:\/\/doi.org\/10.1017\/s0022215112002058","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,19]]}}}