{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:24:12Z","timestamp":1760984652007},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2013,1,2]],"date-time":"2013-01-02T00:00:00Z","timestamp":1357084800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215112002940_sec1\"><jats:title>Aim:<\/jats:title><jats:p>To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215112002940_sec2\"><jats:title>Method:<\/jats:title><jats:p>Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein\u2013Barr viral serology was tested for all patients.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215112002940_sec3\"><jats:title>Results:<\/jats:title><jats:p>Thirty consecutive patients were recruited. Twenty-one patients had normal adenoidal tissue and seven had nasopharyngeal carcinoma. One patient with papillary adenocarcinoma was excluded. The features of narrow-band imaging in normal adenoidal tissue were: (1) a regularly arranged follicular pattern, and (2) each \u2018follicle\u2019 comprising a pale centre with surrounding dark periphery. The features of narrow-band imaging in nasopharyngeal carcinoma were: (1) absence of surface patterns (<jats:italic>n<\/jats:italic>\u00a0=\u00a07), and\/or (2) \u2018reverse\u2019, haphazard follicular pattern comprising a dark brown centre and pale periphery (<jats:italic>n<\/jats:italic>\u00a0=\u00a03).<\/jats:p><\/jats:sec><jats:sec id=\"S0022215112002940_sec4\"><jats:title>Conclusion:<\/jats:title><jats:p>Narrow-band imaging of the surface of adenoidal tissue and nasopharyngeal carcinoma appears to identify distinct, characteristic features as described. Narrow-band imaging may be a useful adjunct in differentiating normal adenoidal tissue from malignancy. Further studies are needed to evaluate its diagnostic accuracy.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215112002940","type":"journal-article","created":{"date-parts":[[2013,1,2]],"date-time":"2013-01-02T14:17:39Z","timestamp":1357136259000},"page":"163-169","source":"Crossref","is-referenced-by-count":12,"title":["Use of narrow-band imaging in detection of nasopharyngeal carcinoma"],"prefix":"10.1017","volume":"127","author":[{"given":"J F","family":"Thong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Loke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Karumathil Sivasankarannair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Mok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,1,2]]},"reference":[{"key":"S0022215112002940_ref5","first-page":"307","article-title":"Reversal of pale-to-dark nasopharyngeal follicle ratio on narrow-band imaging","volume":"16","author":"Vlantis","year":"2010","journal-title":"Hong Kong Med J"},{"key":"S0022215112002940_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2011.02.012"},{"key":"S0022215112002940_ref2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-25285"},{"key":"S0022215112002940_ref9","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.4680"},{"key":"S0022215112002940_ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2008.03802.x"},{"key":"S0022215112002940_ref4","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21310"},{"key":"S0022215112002940_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.09.034"},{"key":"S0022215112002940_ref7","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2011.25.3582"},{"key":"S0022215112002940_ref10","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966214"},{"key":"S0022215112002940_ref1","unstructured":"Seow A , Koh WP , Chia KS , Shi L , Lee HP , Shanmugaratnam K . Trends and incidences of cancer in Singapore 1968\u20132002. In: Ministry of Health. Singapore Cancer Registry Report No. 6. Singapore: Ministry of Health, 2004;88\u20139"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215112002940","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T19:52:47Z","timestamp":1556135567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215112002940\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S0022215112002940"],"URL":"https:\/\/doi.org\/10.1017\/s0022215112002940","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,2]]}}}