{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:25:47Z","timestamp":1763036747485},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T00:00:00Z","timestamp":1365552000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215113000480_sec1\"><jats:title>Objective:<\/jats:title><jats:p>To study the outcome of endonasal endoscopic surgery for adenoid cystic carcinoma of the sinonasal tract over a five-year follow-up period.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000480_sec2\"><jats:title>Design:<\/jats:title><jats:p>Retrospective analysis.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000480_sec3\"><jats:title>Methods:<\/jats:title><jats:p>Four consecutive patients with adenoid cystic carcinoma of the sinonasal tract, who had undergone endonasal endoscopic surgery, were reviewed regarding age at diagnosis, sex, primary site, tumour-node-metastasis staging, treatment modalities, histopathological findings, duration of follow up, distant metastases and treatment outcome.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000480_sec4\"><jats:title>Results:<\/jats:title><jats:p>All patients were diagnosed at an advanced stage and had post-operative adjuvant radiotherapy. Three patients underwent endoscopic endonasal resection and one endoscopic assisted craniofacial resection. The most common primary site was the ethmoid sinus (three patients). Three patients had no evidence of recurrence. One patient who had undergone partial clearance via endoscopic endonasal resection developed cervical node metastases a year after treatment; this patient also developed distant metastases.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000480_sec5\"><jats:title>Conclusion:<\/jats:title><jats:p>Adenoid cystic carcinoma is difficult to treat. Sinonasal tract tumours can be resected via endoscopic endonasal resection or endoscopic assisted craniofacial resection, but prolonged follow up is advisable. Radiotherapy is an important adjuvant treatment.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215113000480","type":"journal-article","created":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T08:23:08Z","timestamp":1365582188000},"page":"511-515","source":"Crossref","is-referenced-by-count":9,"title":["Adenoid cystic carcinoma of the sinonasal tract: outcome of endonasal endoscopic surgery at five-year follow up"],"prefix":"10.1017","volume":"127","author":[{"given":"B S","family":"Gendeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F D","family":"Zahedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T Y","family":"Kew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,4,10]]},"reference":[{"key":"S0022215113000480_ref20","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197807)42:1<265::AID-CNCR2820420141>3.0.CO;2-Z"},{"key":"S0022215113000480_ref18","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920715)70:2<379::AID-CNCR2820700202>3.0.CO;2-C"},{"key":"S0022215113000480_ref11","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790310048012"},{"key":"S0022215113000480_ref4","first-page":"201","article-title":"Adenoid cystic carcinoma of the head and neck: A clinicopathologic study of 37 cases","volume":"24","author":"Haddad","year":"1995","journal-title":"J Otolaryngol"},{"key":"S0022215113000480_ref19","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19840915)54:6<1062::AID-CNCR2820540622>3.0.CO;2-E"},{"key":"S0022215113000480_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(01)00073-6"},{"key":"S0022215113000480_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(71)90440-5"},{"key":"S0022215113000480_ref22","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1097\/PAS.0b013e3180dc928c","article-title":"Adenoid cystic carcinoma with high grade transformation (a report of 11 cases and a review of the literature)","volume":"31","author":"Raja","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"S0022215113000480_ref1","first-page":"218","article-title":"Adenoid cystic carcinoma of the minor salivary glands","volume":"70","author":"Witt","year":"1991","journal-title":"Ear Nose Throat J"},{"key":"S0022215113000480_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(95)00122-F"},{"key":"S0022215113000480_ref7","first-page":"2024","article-title":"Resectability issues with head and neck cancer","volume":"27","author":"Yousem","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"S0022215113000480_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890080309"},{"key":"S0022215113000480_ref13","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000216900.03188.48"},{"key":"S0022215113000480_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-199904000-00007"},{"key":"S0022215113000480_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1994.01880310027006"},{"key":"S0022215113000480_ref3","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1177\/014556130208100810","article-title":"Adenoid cystic carcinoma of the paranasal sinuses or nasal cavity: a 40-year review of 35 cases","volume":"81","author":"Wiseman","year":"2002","journal-title":"Ear Nose Throat J"},{"key":"S0022215113000480_ref10","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/000348949009900102","article-title":"Nonsquamous cell malignancies of the paranasal sinuses","volume":"99","author":"Kraus","year":"1990","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"S0022215113000480_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/BF00051659"},{"key":"S0022215113000480_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(74)90265-7"},{"key":"S0022215113000480_ref23","first-page":"234","article-title":"Endoscopic assisted craniofacial resection: a case series and post-operative outcome","volume":"62","author":"Gendeh","year":"2007","journal-title":"Med J Malaysia"},{"key":"S0022215113000480_ref17","first-page":"2024","article-title":"Resectability issues with head and neck cancer","volume":"27","author":"Yousem","year":"2006","journal-title":"Am J Neurol"},{"key":"S0022215113000480_ref14","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.11.1193"},{"key":"S0022215113000480_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(79)90423-9"},{"key":"S0022215113000480_ref21","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009901215"}],"container-title":["The Journal of Laryngology &amp; 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