{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:02:47Z","timestamp":1762866167073},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2013,4,3]],"date-time":"2013-04-03T00:00:00Z","timestamp":1364947200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Laryngol. Otol."],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0022215113000625_sec1\"><jats:title>Background and objectives:<\/jats:title><jats:p>Organised haematomas of the maxillary sinus are rare, non-neoplastic, haemorrhagic lesions which can extend into the nasal cavity and\/or the other paranasal sinuses. This study aimed to investigate the pathology of maxillary sinus organised haematoma, and also proposes a new aetiological hypothesis based on the observed pathology.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000625_sec2\"><jats:title>Methods:<\/jats:title><jats:p>Biopsies, computed tomography, magnetic resonance imaging and post-surgical histopathological examination of resected specimens were carried out.<\/jats:p><\/jats:sec><jats:sec id=\"S0022215113000625_sec3\"><jats:title>Conclusion:<\/jats:title><jats:p>Distinct pathological differences were observed between the basal and peripheral portions of organised haematomas. We propose that an organised haematoma originates from the exudation of blood components between vascular endothelial cells. As a result, the basal portion consists of aggregated, dilated vessels around the natural ostium of the maxillary sinus. In addition, pseudovessels, without endothelial cells, arise from endocapillary vessels within the haematoma. Exudation of additional blood components from the pseudovessels advances the growth of the organised haematoma.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0022215113000625","type":"journal-article","created":{"date-parts":[[2013,4,3]],"date-time":"2013-04-03T17:11:08Z","timestamp":1365009068000},"page":"519-524","source":"Crossref","is-referenced-by-count":7,"title":["Organised haematoma of the maxillary sinus: pathophysiological differences suggesting a new aetiological hypothesis"],"prefix":"10.1017","volume":"127","author":[{"given":"S","family":"Urata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Ohki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Tsutsumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,4,3]]},"reference":[{"key":"S0022215113000625_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0064-4"},{"key":"S0022215113000625_ref8","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.05.1479"},{"key":"S0022215113000625_ref4","doi-asserted-by":"publisher","DOI":"10.1080\/00016480500316746"},{"key":"S0022215113000625_ref5","first-page":"117","article-title":"Blood boils of the maxillary sinus suspected to be malignant tumors at the first medical examination","volume":"30","author":"Kusunoki","year":"2005","journal-title":"Acta Medical Kinki University"},{"key":"S0022215113000625_ref1","first-page":"359","article-title":"Organized hematoma of the maxillary sinus [in Japanese]","volume":"23","author":"Tadokoro","year":"1917","journal-title":"Dainichijibi"},{"key":"S0022215113000625_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.10.033"},{"key":"S0022215113000625_ref11","first-page":"53","article-title":"Hemangioma of the nasal cavity and sinuses \u2013 a report of twenty-five cases","volume":"49","author":"Ozaki","year":"1977","journal-title":"Otolaryngol Head Neck Surg [Tokyo]"},{"key":"S0022215113000625_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(00)00120-6"},{"key":"S0022215113000625_ref2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310002492"},{"key":"S0022215113000625_ref3","first-page":"929","article-title":"Examination of MRI and histopathological findings of hematocele in the maxillary sinus [in Japanese]","volume":"99","author":"Nagato","year":"2006","journal-title":"Jibirin"},{"key":"S0022215113000625_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2009.06.009"},{"key":"S0022215113000625_ref9","doi-asserted-by":"publisher","DOI":"10.2739\/kurumemedj.55.37"}],"container-title":["The Journal of Laryngology &amp; Otology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022215113000625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T22:09:45Z","timestamp":1556057385000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022215113000625\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,3]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0022215113000625"],"URL":"https:\/\/doi.org\/10.1017\/s0022215113000625","relation":{},"ISSN":["0022-2151","1748-5460"],"issn-type":[{"value":"0022-2151","type":"print"},{"value":"1748-5460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,3]]}}}